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Monica V Motwani

Formats
  1. Meeting Abstract (24)
  2. Journal Article (12)
Groups
  1. GSK Faculty (7)
  2. Sarcoma Surgeons (6)
  3. Surgery (6)
  4. Tow Center for Developmental Oncology (TCDO) (6)
  5. Biostatistics Service (5)
  6. Center for Pancreatic Cancer Research (5)

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People
  1. Gary Schwartz (36)
  2. Francis Sirotnak (8)
  3. Xiaokui Li (8)
  4. Christoph Jung (6)
  5. Manish Shah (6)
  6. Samuel Singer (6)

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Years
  1. 2006 (1)
  2. 2005 (4)
  3. 2004 (4)
  4. 2003 (5)
  5. 2002 (2)
  6. 2001 (8)

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Publications
  1. Clinical Cancer Research (12)
  2. Proceedings of the American Association for Cancer Research Annual Meeting (12)
  3. Cancer Research (5)
  4. Annals of Surgical Oncology (2)
  5. Journal of the American College of Surgeons (2)
  6. Journal of Clinical Oncology (1)

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Publishers
  1. American Association for Cancer Research (30)
  2. Elsevier Science, Inc. (2)
  3. Springer (2)
  4. American Society of Clinical Oncology (1)
  5. The American Society for Pharmacology and Experimental Therapeutics (1)

Results (36)

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  • Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells
    Journal Article

    Sambol, E. B.; Ambrosini, G.; Geha, R. C.; Kennealey, P. T.; Decarolis, P.; O'Connor, R.; Wu, Y. V.; Motwani, M.; Chen, J. H.; Schwartz, G. K.; more...
    Cancer Research (2006)

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  • Flavopiridol is an active agent in the treatment of gastrointestinal stromal tumor (GIST) cells with relative resistance to imatinib mesylate via both transcriptional suppression and inhibition of autophosphorylation of KIT
    Meeting Abstract

    Sambol, E. B.; Motwani, M.; Ambrosini, G.; Geha, R. C.; Decarolis, P.; O'Connor, R.; Chen, J. H.; Schwartz, G. K.; Singer, Samuel
    Cancer Research (2005)

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  • Flavopiridol monotherapy has antiproliferative activity in a panel of soft tissue sarcoma cell lines as well as in vivo antitumor efficacy
    Meeting Abstract

    Sambol, E. B.; Kennealey, P. T.; Motwani, M.; She, Y.; Geha, R. C.; O'Connor, R.; Schwartz, G. K.; Singer, S.
    Annals of Surgical Oncology (2005)

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  • A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol
    Journal Article

    Shah, M. A.; Kortmansky, J.; Motwani, M.; Drobnjak, M.; Gonen, M.; Yi, S.; Weyerbacher, A.; Cordon-Cardo, C.; Lefkowitz, R.; Brenner, B.; more...
    Clinical Cancer Research (2005)

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  • Drg1 expression in 131 colorectal liver metastases: Correlation with clinical variables and patient outcomes
    Journal Article

    Shah, M. A.; Kemeny, N.; Hummer, A.; Drobnjak, M.; Motwani, M.; Cordon-Cardo, C.; Gonen, M.; Schwartz, G. K.
    Clinical Cancer Research (2005)

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  • p53 is a critical element for response to sequential SN-38 (SN) and flavopiridol (F): In vitro studies and clinical correlates
    Meeting Abstract

    Motwani, M. V.; Shah, M. A.; Schwartz, G. K.
    Cancer Research (2004)

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  • Suberoylanilide hydroxamic acid (SAHA), a histone deacetylase (HDAC) inhibitor, induces a unique mitotic effect and potentiates flavopiridol (F) induced apoptosis
    Meeting Abstract

    Cheema, H. S.; Motwani, M. V.; Schwartz, G. K.
    Cancer Research (2004)

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  • Flavopiridol inhibits soft tissue sarcoma growth with preferential sensitivity in a Cdk4 gene amplified subtype
    Meeting Abstract

    Sambol, E. B.; Kennealey, P. T.; Motwani, M.; Chen, J. H.; Cheema, H.; Leversha, M.; Schwartz, G. K.; Singer, S.
    Journal of the American College of Surgeons (2004)

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  • Flavopiridol potentiates effect of oxaliplatin in vitro and in vivo and requires intact p53
    Meeting Abstract

    Motwani, M. V.; Racanelli, A.; Schwartz, G. K.
    Journal of Clinical Oncology (2004)

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  • Transcriptional up-regulation of pre-m-RNA splicing factor Srp20: A novel mechanism of flavopiridol induced apoptosis in human colon cancer cells
    Meeting Abstract

    Motwani, M. V.; Cheema, H. S.; Sridhar, P.; Sirotnak, F. M.; Schwartz, G. K.
    Proceedings of the American Association for Cancer Research Annual Meeting (2003)

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