Flavopiridol is an active agent in the treatment of gastrointestinal stromal tumor (GIST) cells with relative resistance to imatinib mesylate via both transcriptional suppression and inhibition of autophosphorylation of KIT Meeting Abstract


Authors: Sambol, E. B.; Motwani, M.; Ambrosini, G.; Geha, R. C.; Decarolis, P.; O'Connor, R.; Chen, J. H.; Schwartz, G. K.; Singer, Samuel
Abstract Title: Flavopiridol is an active agent in the treatment of gastrointestinal stromal tumor (GIST) cells with relative resistance to imatinib mesylate via both transcriptional suppression and inhibition of autophosphorylation of KIT
Meeting Title: 96th Annual Meeting of the American Association for Cancer Research (AACR)
Keywords: drug resistance; transcriptional suppression; autophosphorylation inhibition
Journal Title: Cancer Research
Volume: 65
Issue: 9 Suppl.
Meeting Dates: 2005 Apr 16-20
Meeting Location: Anaheim, CA
ISSN: 0008-5472
Publisher: American Association for Cancer Research  
Date Published: 2005-05-01
Start Page: 352
End Page: 353
Language: English
ACCESSION: BIOSIS:PREV200700269601
PROVIDER: biosis
DOI/URL:
Notes: Meeting abstract: 1504 -- In: Proceedings of the 96th Annual Meeting of the American Association for Cancer Research -- Anaheim, CA, USA -- April 16 -20, 2005 -- Amer Assoc Canc Res -- Source: Biosis
MSK Authors
  1. Elliot Brett Sambol
    14 Sambol
  2. Rula Christine Geha
    11 Geha
  3. Gary Schwartz
    385 Schwartz
  4. Monica V Motwani
    36 Motwani
  5. Jinhong Chen
    17 Chen
  6. Samuel Singer
    337 Singer