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Chul Bom Lee

Formats
  1. Journal Article (7)
Groups
  1. Molecular Pharmacology and Chemistry Program Faculty (7)
  2. Sloan Kettering Institute Faculty (7)
  3. Sloan Kettering Institute Postdocs (7)
People
  1. Samuel Danishefsky (7)
  2. Shawn Stachel (7)
  3. Mark Chappell (6)
  4. Ting-Chao Chou (6)
  5. Yongbiao Guan (4)
  6. Scott Kuduk (2)

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Years
  1. 2002 (1)
  2. 2001 (3)
  3. 2000 (3)
Publications
  1. Journal of Organic Chemistry (3)
  2. Organic Letters (2)
  3. Journal of the American Chemical Society (1)
  4. Proceedings of the National Academy of Sciences of the United States of America (1)
Publishers
  1. American Chemical Society (6)
  2. National Academy of Sciences (1)

Results (7)

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  • Probing the SAR of dEpoB via chemical synthesis: A total synthesis evaluation of C26-(1,3-dioxolanyl)-12,13-desoxyepothilone B
    Journal Article

    Chappell, M. D.; Harris, C. R.; Kuduk, S. D.; Balog, A.; Wu, Z.; Zhang, F.; Lee, C. B.; Stachel, S. J.; Danishefsky, S. J.; Chou, T. C.; more...
    Journal of Organic Chemistry (2002)

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  • The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: Curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice
    Journal Article

    Chou, T. C.; O'Connor, O. A.; Tong, W. P.; Guan, Y.; Zhang, Z. G.; Stachel, S. J.; Lee, C.; Danishefsky, S. J.
    Proceedings of the National Academy of Sciences of the United States of America (2001)

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  • Insights into long-range structural effects on the stereochemistry of aldol condensations: A practical total synthesis of desoxyepothilone F
    Journal Article

    Lee, C. B.; Wu, Z.; Zhang, F.; Chappell, M. D.; Stachel, S. J.; Chou, T. C.; Guan, Y.; Danishefsky, S. J.
    Journal of the American Chemical Society (2001)

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  • On the interactivity of complex synthesis and tumor pharmacology in the drug discovery process: Total synthesis and comparative in vivo evaluations of the 15-aza epothilones
    Journal Article

    Stachel, S. J.; Lee, C. B.; Spassova, M.; Chappell, M. D.; Bornmann, W. G.; Danishefsky, S. J.; Chou, T. C.; Guan, Y.
    Journal of Organic Chemistry (2001)

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  • On the total synthesis and preliminary biological evaluations of 15(R) and 15(S) aza-dEpoB: A Mitsunobu inversion at C15 in pre-epothilone fragments
    Journal Article

    Stachel, S. J.; Chappell, M. D.; Lee, C. B.; Danishefsky, S. J.; Chou, T. C.; He, L.; Horwitz, S. B.
    Organic Letters (2000)

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  • En route to a plant scale synthesis of the promising antitumor agent 12,13-desoxyepothilone B
    Journal Article

    Chappell, M. D.; Stachel, S. J.; Lee, C. B.; Danishefsky, S. J.
    Organic Letters (2000)

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  • Total synthesis and antitumor activity of 12,13-desoxyepothilone F: An unexpected solvolysis problem at C15, mediated by remote substitution at C21
    Journal Article

    Lee, C. B.; Chou, T. C.; Zhang, X.; Wang, Z. G.; Kuduk, S. D.; Chappell, M. D.; Stachel, S. J.; Danishefsky, S. J.
    Journal of Organic Chemistry (2000)

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