En route to a plant scale synthesis of the promising antitumor agent 12,13-desoxyepothilone B Journal Article
| Authors: | Chappell, M. D.; Stachel, S. J.; Lee, C. B.; Danishefsky, S. J. |
| Article Title: | En route to a plant scale synthesis of the promising antitumor agent 12,13-desoxyepothilone B |
| Abstract: | (Equation Presented) A 12,13-desoxyepothilone B dEpoB Efficient and processable syntheses of key building blocks of the antitumor agent 12,13-desoxyepothilone B (dEpoB) by catalytic asymmetric induction are herein described. |
| Keywords: | antineoplastic agents; antineoplastic agent; economics; chemistry; thiazoles; synthesis; epothilones; epothilone b; epothilone derivative; epoxy compounds; lactones; thiazole derivative; lactone; epoxide; article; desoxyepothilone b |
| Journal Title: | Organic Letters |
| Volume: | 2 |
| Issue: | 11 |
| ISSN: | 1523-7060 |
| Publisher: | American Chemical Society |
| Date Published: | 2000-06-01 |
| Start Page: | 1633 |
| End Page: | 1636 |
| Language: | English |
| PUBMED: | 10841497 |
| PROVIDER: | scopus |
| DOI: | 10.1021/ol0059302 |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
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