Chemo- and stereoselective epoxidation of 12,13-desoxyepothilone B using 2,2′-dimethyldioxirane Journal Article


Authors: Stachel, S. J.; Danishefsky, S. J.
Article Title: Chemo- and stereoselective epoxidation of 12,13-desoxyepothilone B using 2,2′-dimethyldioxirane
Abstract: Epoxidation of 12,13-desoxyepothilone B (dEpoB) to epothilone B (EpoB), using DMDO, reproducibly gives excellent stereoselectivity with high confidence and yield. © 2001 Published by Elsevier Science Ltd.
Keywords: unclassified drug; drug structure; reaction analysis; chemical reaction; stereochemistry; epothilone b; stoichiometry; epoxidation; 12,13 desoxyepothilone b; article; 2,2' dimethyldioxirane; dimethyldioxirane
Journal Title: Tetrahedron Letters
Volume: 42
Issue: 39
ISSN: 0040-4039
Publisher: Pergamon-Elsevier Science Ltd  
Date Published: 2001-09-24
Start Page: 6785
End Page: 6787
Language: English
DOI: 10.1016/s0040-4039(01)01209-6
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
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  1. Shawn J Stachel
    13 Stachel