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Ligeng Tian

Formats
  1. Journal Article (8)
Groups
  1. Basic Research Innovation Award (BRIA) (8)
  2. GSK Faculty (8)
  3. Molecular Biology Program Faculty (8)
  4. Sloan Kettering Institute Faculty (8)
People
  1. Stewart Shuman (8)
  2. Lyudmila Yakovleva (1)
  3. Yi Pei (1)
Years
  1. 2007 (1)
  2. 2005 (1)
  3. 2004 (2)
  4. 2003 (3)
  5. 2000 (1)
Publications
  1. Journal of Biological Chemistry (3)
  2. Structure (2)
  3. Molecular Cell (1)
  4. Nucleic Acids Research (1)
  5. Virology (1)
Publishers
  1. American Society for Biochemistry and Molecular Biology (3)
  2. Cell Press (3)
  3. Elsevier Inc. (1)
  4. Oxford University Press (1)

Results (8)

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  • Vaccinia topoisomerase mutants illuminate roles for Phe59, Gly73, Gln69 and Phe215
    Journal Article

    Tian, L.; Shuman, S.
    Virology (2007)

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  • Mechanistic plasticity of DNA topoisomerase IB: Phosphate electrostatics dictate the need for a catalytic arginine
    Journal Article

    Tian, L.; Claeboe, C. D.; Hecht, S. M.; Shuman, S.
    Structure (2005)

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  • Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB
    Journal Article

    Tian, L.; Claeboe, C. D.; Hecht, S. M.; Shuman, S.
    Structure (2004)

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  • Individual nucleotide bases, not base pairs, are critical for triggering site-specific DNA cleavage by vaccinia topoisomerase
    Journal Article

    Tian, L.; Sayer, J. M.; Jerina, D. M.; Shuman, S.
    Journal of Biological Chemistry (2004)

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  • Site-specific DNA transesterification by vaccinia topoisomerase: Effects of benzo[a]pyrene-dA, 8-oxoguanine, 8-oxoadenine, and 2-aminopurine modifications
    Journal Article

    Yakovleva, L.; Tian, L.; Sayer, J. M.; Kalena, G. P.; Kroth, H.; Jerina, D. M.; Shuman, S.
    Journal of Biological Chemistry (2003)

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  • Benzo[a]pyrene-dG adduct interference illuminates the interface of vaccinia topoisomerase with the DNA minor groove
    Journal Article

    Tian, L.; Sayer, J. M.; Kroth, H.; Kalena, G.; Jerina, D. M.; Shuman, S.
    Journal of Biological Chemistry (2003)

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  • Guarding the genome: Electrostatic repulsion of water by DNA suppresses a potent nuclease activity of topoisomerase IB
    Journal Article

    Tian, L.; Claeboe, C. D.; Hecht, S. M.; Shuman, S.
    Molecular Cell (2003)

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  • Characterization of Candida albicans RNA triphosphatase and mutational analysis of its active site
    Journal Article

    Pei, Y.; Lehman, K.; Tian, L.; Shuman, S.
    Nucleic Acids Research (2000)

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