Synapse - Guilherme Harada

Results (30)

Activating mutations in the MET kinase domain co-occur with other driver oncogenes and mediate resistance to targeted therapy in NSCLC

Journal Article

Nakazawa, S.; Pecci, F.; Ricciuti, B.; Gottlieb, F. H.; Facchinetti, F.; Harada, G.; Chen, M. F.; Repetto, M.; Giacomini, F.; Jiang, J.; more...
Journal of Thoracic Oncology (2025)

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A phase II study of cabozantinib in patients with MET-altered lung cancers

Journal Article

Harada, G.; Santini, F. C.; Wilhelm, C. J.; Repetti, R. W.; Chang, J. C.; Yang, S. R.; Lin, Y. T.; Moses, K. A.; Falcon, C.; Goldstein, M.; more...
JTO Clinical and Research Reports (2025)

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Sarcoid-like reactions in patients treated with checkpoint inhibitors for advanced solid tumors

Journal Article

Nykaza, I.; Murciano-Goroff, Y. R.; Desilets, A.; Harada, G.; Postow, M. A.; Callahan, M. K.; Lee, C. H.; Rudin, C. M.; Kelsen, D. P.; Stadler, Z. K.; more...
The Oncologist (2025)

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Mucocutaneous adverse events in patients with cancer treated with the highly selective RET kinase inhibitor selpercatinib (LOXO-292)

Journal Article

Reingold, R. E.; Parisi, R.; Harada, G.; Moy, A. P.; Dranitsaris, G.; Francis, J. H.; Canestraro, J.; Lester, J. A.; Kaplanis, L. A.; Liu, D.; more...
JTO Clinical and Research Reports (2025)

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Clinical characteristics and outcomes of central nervous system tumors harboring NTRK gene fusions

Journal Article

Lamoureux, A. A.; Fisher, M. J.; Lemelle, L.; Pfaff, E.; Amir-Yazdani, P.; Kramm, C.; De Wilde, B.; Kazanowska, B.; Hutter, C.; Pfister, S. M.; more...
Clinical Cancer Research (2025)

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BRAF variants and oncogenic fusions to define sporadic MMR-deficient colorectal cancer subtypes

Meeting Abstract

Abdelfattah, S.; Harada, G.; Patel, S.; Artz, O.; Yaeger, R.; Johannet, P.; Harrold, E.; Walch, H. S.; Argiles, G.; Rousseau, B.; more...
Journal of Clinical Oncology (2024)

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Basket trials: Past, present, and future

Review

Murciano-Goroff, Y. R.; Uppal, M.; Chen, M.; Harada, G.; Schram, A. M.
Annual Review of Cancer Biology (2024)

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Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents

Journal Article

Roa, P.; Foglizzo, V.; Harada, G.; Repetto, M.; Kulick, A.; de Stanchina, E.; de Marchena, M.; Auwardt, S.; Sayed Ahmed, S.; Bremer, N. V.; more...
British Journal of Cancer (2024)

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TKI type switching overcomes ROS1 L2086F in ROS1 fusion-positive cancers

Journal Article

Thawani, R.; Repetto, M.; Keddy, C.; Nicholson, K.; Jones, K.; Nusser, K.; Beach, C. Z.; Harada, G.; Drilon, A.; Davare, M. A.
npj Precision Oncology (2024)

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Activating point mutations in the MET kinase domain represent a unique molecular subset of lung cancer and other malignancies targetable with MET inhibitors

Journal Article

Pecci, F.; Nakazawa, S.; Ricciuti, B.; Harada, G.; Lee, J. K.; Alessi, J. V.; Barrichello, A.; Vaz, V. R.; Lamberti, G.; Di Federico, A.; more...
Cancer Discovery (2024)

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