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Mark C. Waltham

Formats
  1. Journal Article (14)
  2. Meeting Abstract (6)
  3. Conference Paper (3)
Groups
  1. Center for Hematologic Malignancies (4)
  2. Hematologic Malignancies Service (3)
  3. Pediatric Leukemia (3)
  4. Pediatrics, Department of (3)
  5. Department of Medicine (2)
  6. Hematologic Malignancies, Division of (2)

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People
  1. Joseph Bertino (22)
  2. Debabrata Banerjee (12)
  3. Emine Ercikan (8)
  4. Weiwei Li (8)
  5. Barry Schweitzer (7)
  6. Erdem Goker (7)

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Years
  1. 1997 (3)
  2. 1996 (5)
  3. 1995 (5)
  4. 1994 (3)
  5. 1993 (6)
  6. 1992 (1)
Publications
  1. Proceedings of the American Association for Cancer Research Annual Meeting (4)
  2. Advances in Experimental Medicine and Biology (3)
  3. Molecular Pharmacology (3)
  4. Blood (2)
  5. Acta Biochimica Polonica (1)
  6. Biochemistry (1)

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Publishers
  1. American Association for Cancer Research (5)
  2. Springer (3)
  3. The American Society for Pharmacology and Experimental Therapeutics (3)
  4. American Chemical Society (2)
  5. American Society of Hematology (2)
  6. Elsevier Science, Inc. (2)

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Results (23)

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  • Molecular mechanisms of resistance to antifolates, a review
    Journal Article

    Banerjee, D.; Ercikan-Abali, E.; Waltham, M.; Schnieders, B.; Hochhauser, D.; Li, W. W.; Fan, J.; Gorlick, R.; Goker, E.; Bertino, J. R.
    Acta Biochimica Polonica (1995)

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  • Acute monocytic leukemia: A myeloid leukemia subset that may be sensitive to methotrexate
    Journal Article

    Göker, E.; Kheradpour, A.; Waltham, M.; Banerjee, D.; Tong, W. P.; Elisseyeff, Y.; Bertino, J. R.
    Leukemia (1995)

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  • 2,4-diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii
    Journal Article

    Rosowsky, A.; Mota, C. E.; Queener, S. F.; Waltham, M.; Ercikan-Abali, E.; Bertino, J. R.
    Journal of Medicinal Chemistry (1995)

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  • Capillary electrophoresis of methotrexate polyglutamates and its application in evaluation of folylpolyglutamate hydrolase activity
    Meeting Abstract

    Tong, W. P.; Lin, S.; Li, W. W.; Waltham, M.; Goker, E.; Bertino, J. R.
    Proceedings of the American Association for Cancer Research Annual Meeting (1994)

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  • Transfection with a cDNA encoding a Ser(31) or Ser(34) mutant human dihydrofolate reductase into Chinese hamster ovary and mouse marrow progenitor cells confers methotrexate resistance
    Journal Article

    Banerjee, D.; Schweitzer, B. I.; Volkenandt, M.; Li, M. X.; Waltham, M.; Mineishi, S.; Zhao, S. C.; Bertino, J. R.
    Gene (1994)

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  • Ab initio studies of 2,4-diamino triazine and its complexes with ligands: A model for inhibitor-active site interactions of dihydrofolate reductase
    Journal Article

    Sapse, A. M.; Waltham, M. C.; Bertino, J. R.
    Cancer Investigation (1994)

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  • Dihydrofolate-reductase (DHFR) gene amplification in acute lymphoblastic leukemia (ALL) blasts resistant to methotrexate (MTX) is associated with mutations in the p53 gene
    Meeting Abstract

    Goker, E.; Kheradpour, A.; Trippett, T.; Waltham, M.; Elisseyeff, Y.; Schnieders, B.; Bertino, J. R.
    Blood (1993)

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  • Effect of codon 22 mutations on substrate and inhibitor binding for human dihydrofolate reductase
    Conference Paper

    Ercikan, E.; Waltham, M.; Dicker, A.; Schweitzer, B.; Bertino, J. R.
    Springer (1993)

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  • Increased activity of γ-glutamyl hydrolase in human sarcoma cell lines: A novel mechanism of intrinsic resistance to methotrexate (MTX)
    Conference Paper

    Li, W. W.; Waltham, M.; Tong, W.; Schweitzer, B. I.; Bertino, J. R.
    Springer (1993)

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  • Translational regulation of the synthesis of dihydrofolate reductase
    Conference Paper

    Ercikan, E.; Banerjee, D.; Waltham, M.; Schnieders, B.; Scotto, K. W.; Bertino, J. R.
    Springer (1993)

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