Increased activity of γ-glutamyl hydrolase in human sarcoma cell lines: A novel mechanism of intrinsic resistance to methotrexate (MTX) Conference Paper


Authors: Li, W. W.; Waltham, M.; Tong, W.; Schweitzer, B. I.; Bertino, J. R.
Title: Increased activity of γ-glutamyl hydrolase in human sarcoma cell lines: A novel mechanism of intrinsic resistance to methotrexate (MTX)
Conference Title: 10th International Symposium on Chemistry and Biology of Pteridines
Keywords: controlled study; human cell; conference paper; comparative study; methotrexate; cell line; enzyme activation; drug resistance; tumor cells, cultured; kinetics; soft tissue sarcoma; lymphatic leukemia; glutamic acid; hydrogen-ion concentration; leukemia cell line; gamma-glutamyl hydrolase; polyglutamic acid; hydrolase; lymphoblastoid cell; leukemia, lymphocytic; human; priority journal; folylpolyglutamate synthase
Journal Title Advances in Experimental Medicine and Biology
Volume: 338
Conference Dates: 1993 Mar 21-26
Conference Location: Orange Beach, AL
ISBN: 0065-2598
Publisher: Springer  
Date Published: 1993-01-01
Start Page: 635
End Page: 638
Language: English
PUBMED: 7508171
PROVIDER: scopus
DOI: 10.1007/978-1-4615-2960-6_131
DOI/URL:
Notes: Chapter in "Chemistry and Biology of Pteridines and Folates" (ISBN: 978-1-4613-6287-6) -- Source: Scopus
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MSK Authors
  1. Weiwei Li
    63 Li
  2. William Ping-Yiu Tong
    158 Tong
  3. Joseph Bertino
    363 Bertino
  4. Mark C. Waltham
    23 Waltham