Authors: | Li, W. W.; Waltham, M.; Tong, W.; Schweitzer, B. I.; Bertino, J. R. |
Title: | Increased activity of γ-glutamyl hydrolase in human sarcoma cell lines: A novel mechanism of intrinsic resistance to methotrexate (MTX) |
Conference Title: | 10th International Symposium on Chemistry and Biology of Pteridines |
Keywords: | controlled study; human cell; conference paper; comparative study; methotrexate; cell line; enzyme activation; drug resistance; tumor cells, cultured; kinetics; soft tissue sarcoma; lymphatic leukemia; glutamic acid; hydrogen-ion concentration; leukemia cell line; gamma-glutamyl hydrolase; polyglutamic acid; hydrolase; lymphoblastoid cell; leukemia, lymphocytic; human; priority journal; folylpolyglutamate synthase |
Journal Title | Advances in Experimental Medicine and Biology |
Volume: | 338 |
Conference Dates: | 1993 Mar 21-26 |
Conference Location: | Orange Beach, AL |
ISBN: | 0065-2598 |
Publisher: | Springer |
Date Published: | 1993-01-01 |
Start Page: | 635 |
End Page: | 638 |
Language: | English |
PUBMED: | 7508171 |
PROVIDER: | scopus |
DOI: | 10.1007/978-1-4615-2960-6_131 |
DOI/URL: | |
Notes: | Chapter in "Chemistry and Biology of Pteridines and Folates" (ISBN: 978-1-4613-6287-6) -- Source: Scopus |