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Bess Peninna Rosen

Formats
  1. Journal Article (7)
  2. Research Letter (1)
  3. Review (1)
Groups
  1. Basic Research Innovation Award (BRIA) (9)
  2. Center for Molecular Imaging and Biotechnology (CMIB) (9)
  3. Center for Pancreatic Cancer Research (9)
  4. Developmental Biology Program Faculty (9)
  5. GSK Faculty (9)
  6. MSK Grad Students (9)

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People
  1. Danwei Huangfu (9)
  2. Dapeng Yang (6)
  3. Qing Li (5)
  4. Renhe Luo (5)
  5. Dingyu Liu (3)
  6. Gary Dixon (3)

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Years
  1. 2025 (2)
  2. 2024 (1)
  3. 2023 (1)
  4. 2022 (1)
  5. 2021 (1)
  6. 2020 (1)

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Publications
  1. Nature Cell Biology (2)
  2. Nature Genetics (2)
  3. Nature Communications (1)
  4. Nature Metabolism (1)
  5. Science (1)
  6. Stem Cell Reports (1)

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Publishers
  1. Nature Publishing Group (6)
  2. American Association for the Advancement of Science (1)
  3. Cell Press (1)
  4. Wiley Blackwell (1)

Results (9)

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  • Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells
    Journal Article

    Yan, J.; Luo, R.; Rosen, B. P.; Liu, D.; Wong, W.; Leslie, C. S.; Huangfu, D.
    Stem Cell Reports (2025)

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  • Decoding heterogeneous single-cell perturbation responses
    Journal Article

    Song, B.; Liu, D.; Dai, W.; McMyn, N. F.; Wang, Q.; Yang, D.; Krejci, A.; Vasilyev, A.; Untermoser, N.; Loregger, A.; more...
    Nature Cell Biology (2025)

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  • Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness
    Journal Article

    Rosen, B. P.; Li, Q. V.; Cho, H. S.; Liu, D.; Yang, D.; Graff, S.; Yan, J.; Luo, R.; Verma, N.; Damodaran, J. R.; more...
    Nature Communications (2024)

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  • Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions
    Journal Article

    Luo, R.; Yan, J.; Oh, J. W.; Xi, W.; Shigaki, D.; Wong, W.; Cho, H. S.; Murphy, D.; Cutler, R.; Rosen, B. P.; more...
    Nature Genetics (2023)

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  • CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction
    Journal Article

    Yang, D.; Cho, H.; Tayyebi, Z.; Shukla, A.; Luo, R.; Dixon, G.; Ursu, V.; Stransky, S.; Tremmel, D. M.; Sackett, S. D.; more...
    Nature Cell Biology (2022)

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  • QSER1 protects DNA methylation valleys from de novo methylation
    Journal Article

    Dixon, G.; Pan, H.; Yang, D.; Rosen, B. P.; Jashari, T.; Verma, N.; Pulecio, J.; Caspi, I.; Lee, K.; Stransky, S.; more...
    Science (2021)

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  • Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency
    Review

    Li, Q. V.; Rosen, B. P.; Huangfu, D.
    Wiley Interdisciplinary Reviews: Systems Biology and Medicine (2020)

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  • Glutamine independence is a selectable feature of pluripotent stem cells
    Research Letter

    Vardhana, S. A.; Arnold, P. K.; Rosen, B. P.; Chen, Y.; Carey, B. W.; Huangfu, D.; Carmona-Fontaine, C.; Thompson, C. B.; Finley, L. W. S.
    Nature Metabolism (2019)

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  • Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation
    Journal Article

    Li, Q. V.; Dixon, G.; Verma, N.; Rosen, B. P.; Gordillo, M.; Luo, R.; Xu, C.; Wang, Q.; Soh, C. L.; Yang, D.; more...
    Nature Genetics (2019)

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