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Douglas Robert Hoen

Formats
  1. Journal Article (7)
  2. Research Letter (2)
  3. Meeting Abstract (1)
Groups
  1. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (10)
  2. GSK Faculty (10)
  3. Sloan Kettering Institute Postdocs (10)
  4. Surgery (10)
  5. Department of Medicine (8)
  6. Human Oncology and Pathogenesis Program (8)

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People
  1. Timothy Chan (9)
  2. Luc Morris (8)
  3. Abraham Hakimi (6)
  4. Cristina Valero Mayor (5)
  5. Fengshen Kuo (5)
  6. Mark Lee (5)

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Years
  1. 2022 (1)
  2. 2021 (5)
  3. 2020 (2)
  4. 2019 (2)
Publications
  1. Nature Communications (2)
  2. Immunity (1)
  3. JAMA Oncology (1)
  4. Journal of Clinical Oncology (1)
  5. Molecular Cancer Research (1)
  6. Nature Biotechnology (1)

More Publications

Publishers
  1. Nature Publishing Group (5)
  2. American Association for Cancer Research (1)
  3. American Medical Association (1)
  4. American Society of Clinical Oncology (1)
  5. Cell Press (1)
  6. Nature Research (1)

Results (10)

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  • Improved prediction of immune checkpoint blockade efficacy across multiple cancer types
    Journal Article

    Chowell, D.; Yoo, S. K.; Valero, C.; Pastore, A.; Krishna, C.; Lee, M.; Hoen, D.; Shi, H.; Kelly, D. W.; Patel, N.; more...
    Nature Biotechnology (2022)

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  • High response rate and durability driven by HLA genetic diversity in patients with kidney cancer treated with lenvatinib and pembrolizumab
    Journal Article

    Lee, C. H.; DiNatale, R. G.; Chowell, D.; Krishna, C.; Makarov, V.; Valero, C.; Vuong, L.; Lee, M.; Weiss, K.; Hoen, D.; more...
    Molecular Cancer Research (2021)

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  • Response rates to anti-PD-1 immunotherapy in microsatellite-stable solid tumors with 10 or more mutations per megabase
    Journal Article

    Valero, C.; Lee, M.; Hoen, D.; Zehir, A.; Berger, M. F.; Seshan, V. E.; Chan, T. A.; Morris, L. G. T.
    JAMA Oncology (2021)

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  • Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    Journal Article

    Tello-Lafoz, M.; Srpan, K.; Sanchez, E. E.; Hu, J.; Remsik, J.; Romin, Y.; Calò€, A.; Hoen, D.; Bhanot, U.; Morris, L.; more...
    Immunity (2021)

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  • Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors
    Journal Article

    Valero, C.; Lee, M.; Hoen, D.; Weiss, K.; Kelly, D. W.; Adusumilli, P. S.; Paik, P. K.; Plitas, G.; Ladanyi, M.; Postow, M. A.; more...
    Nature Communications (2021)

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  • The association between tumor mutational burden and prognosis is dependent on treatment context
    Research Letter

    Valero, C.; Lee, M.; Hoen, D.; Wang, J.; Nadeem, Z.; Patel, N.; Postow, M. A.; Shoushtari, A. N.; Plitas, G.; Balachandran, V. P.; more...
    Nature Genetics (2021)

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  • Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy
    Journal Article

    Samstein, R. M.; Krishna, C.; Ma, X.; Pei, X.; Lee, K. W.; Makarov, V.; Kuo, F.; Chung, J.; Srivastava, R. M.; Purohit, T. A.; more...
    Nature Cancer (2020)

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  • A pan-cancer analysis of PBAF complex mutations and their association with immunotherapy response
    Journal Article

    Hakimi, A. A.; Attalla, K.; DiNatale, R. G.; Ostrovnaya, I.; Flynn, J.; Blum, K. A.; Ged, Y.; Hoen, D.; Kendall, S. M.; Reznik, E.; more...
    Nature Communications (2020)

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  • The impact of PBRM1 mutations on overall survival in greater than 2,100 patients treated with immune checkpoint blockade (ICB)
    Meeting Abstract

    Hakimi, A. A.; Ged, Y.; Flynn, J.; Hoen, D. R.; Di Natale, R. G.; Blum, K. A.; Makarov, V.; Kuo, F.; Carlo, M. I.; Lee, C. H.; more...
    Journal of Clinical Oncology (2019)

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  • Immunogenic neoantigens derived from gene fusions stimulate T cell responses
    Research Letter

    Yang, W.; Lee, K. W.; Srivastava, R. M.; Kuo, F.; Krishna, C.; Chowell, D.; Makarov, V.; Hoen, D.; Dalin, M. G.; Wexler, L.; more...
    Nature Medicine (2019)

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