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Rajendra Uprety

Formats
  1. Journal Article (14)
  2. Meeting Abstract (2)
Groups
  1. Sloan Kettering Institute Postdocs (16)
  2. Molecular Pharmacology and Chemistry Program Faculty (10)
  3. Sloan Kettering Institute Faculty (10)
  4. Anesthesiology Service (1)
  5. Anesthesiology and Critical Care Medicine (1)
People
  1. Gavril Pasternak (10)
  2. Susruta Majumdar (8)
  3. Valerie Le Rouzic (6)
  4. Yingxian Pan (6)
  5. Amanda Hunkele (5)
  6. Andras Varadi (5)

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Years
  1. 2021 (6)
  2. 2020 (3)
  3. 2019 (4)
  4. 2018 (3)
Publications
  1. Neuropharmacology (3)
  2. British Journal of Pharmacology (2)
  3. Cellular and Molecular Neurobiology (2)
  4. Journal of Medicinal Chemistry (2)
  5. ACS Central Science (1)
  6. ACS Chemical Neuroscience (1)

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Publishers
  1. American Chemical Society (4)
  2. Pergamon-Elsevier Science Ltd (3)
  3. Wiley Blackwell (3)
  4. Springer (2)
  5. Cell Press (1)
  6. Elsevier Inc. (1)

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Results (16)

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  • Oxidative metabolism as a modulator of kratom's biological actions
    Journal Article

    Chakraborty, S.; Uprety, R.; Slocum, S. T.; Irie, T.; Le Rouzic, V.; Li, X.; Wilson, L. L.; Scouller, B.; Alder, A. F.; Kruegel, A. C.; more...
    Journal of Medicinal Chemistry (2021)

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  • Kratom alkaloids as probes for opioid receptor function: Pharmacological characterization of minor indole and oxindole alkaloids from kratom
    Journal Article

    Chakraborty, S.; Uprety, R.; Daibani, A. E.; Rouzic, V. L.; Hunkele, A.; Appourchaux, K.; Eans, S. O.; Nuthikattu, N.; Jilakara, R.; Thammavong, L.; more...
    ACS Chemical Neuroscience (2021)

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  • Kratom alkaloids, natural and semi-synthetic, show less physical dependence and ameliorate opioid withdrawal
    Journal Article

    Wilson, L. L.; Chakraborty, S.; Eans, S. O.; Cirino, T. J.; Stacy, H. M.; Simons, C. A.; Uprety, R.; Majumdar, S.; McLaughlin, J. P.
    Cellular and Molecular Neurobiology (2021)

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  • Synthesis and characterization of azido aryl analogs of IBNtxA for radio-photoaffinity labeling opioid receptors in cell lines and in mouse brain
    Journal Article

    Grinnell, S. G.; Uprety, R.; Varadi, A.; Subrath, J.; Hunkele, A.; Pan, Y. X.; Pasternak, G. W.; Majumdar, S.
    Cellular and Molecular Neurobiology (2021)

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  • Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
    Journal Article

    Uprety, R.; Che, T.; Zaidi, S. A.; Grinnell, S. G.; Varga, B. R.; Faouzi, A.; Slocum, S. T.; Allaoa, A.; Varadi, A.; Nelson, M.; more...
    eLife (2021)

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  • The mixed kappa and delta opioid receptor agonist, MP1104, attenuates chemotherapy-induced neuropathic pain
    Journal Article

    Atigari, D. V.; Paton, K. F.; Uprety, R.; Váradi, A.; Alder, A. F.; Scouller, B.; Miller, J. H.; Majumdar, S.; Kivell, B. M.
    Neuropharmacology (2021)

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  • Synthesis and pharmacology of a novel μ-δ opioid receptor heteromer-selective agonist based on the carfentanyl template
    Journal Article

    Faouzi, A.; Uprety, R.; Gomes, I.; Massaly, N.; Keresztes, A. I.; Le Rouzic, V.; Gupta, A.; Zhang, T.; Yoon, H. J.; Ansonoff, M.; more...
    Journal of Medicinal Chemistry (2020)

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  • G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder
    Journal Article

    Gutridge, A. M.; Robins, M. T.; Cassell, R. J.; Uprety, R.; Mores, K. L.; Ko, M. J.; Pasternak, G. W.; Majumdar, S.; van Rijn, R. M.
    British Journal of Pharmacology (2020)

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  • The antinociceptive effects of a dual kappa-delta opioid receptor agonist in the mouse formalin test
    Journal Article

    Ulker, E.; Toma, W.; White, A.; Uprety, R.; Majumdar, S.; Damaj, M. I.
    Behavioural Pharmacology (2020)

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  • Plant-derived biased opioids show utility in the reduction of drinking behaviour in C57BL/6 mice
    Meeting Abstract

    Cassell, R. J.; Mores, K. L.; Robins, M. T.; Gutridge, A. M.; Uprety, R.; Zerfas, B. L.; Trader, D. J.; Majumdar, S.; van Rijn, R. M.
    British Journal of Pharmacology (2019)

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