Synapse - Sahil Sharma

Results (31)

Targeting stressor-induced dysfunctions in protein–protein interaction networks via epichaperomes

Editorial

Ginsberg, S. D.; Sharma, S.; Norton, L.; Chiosis, G.
Trends in Pharmacological Sciences (2023)

Disease-specific interactome alterations via epichaperomics: The case for Alzheimer’s disease

Review

Ginsberg, S. D.; Neubert, T. A.; Sharma, S.; Digwal, C. S.; Yan, P.; Timbus, C.; Wang, T.; Chiosis, G.
FEBS Journal (2022)

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Synthesis of (124)I-labeled epichaperome probes and assessment in visualizing pathologic protein-protein interaction networks in tumor bearing mice

Journal Article

Sharma, S.; Kalidindi, T.; Joshi, S.; Digwal, C. S.; Panchal, P.; Burnazi, E.; Lee, S. G.; Pillarsetty, N.; Chiosis, G.
STAR Protocols (2022)

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The penalty of stress - Epichaperomes negatively reshaping the brain in neurodegenerative disorders

Review

Ginsberg, S. D.; Joshi, S.; Sharma, S.; Guzman, G.; Wang, T.; Arancio, O.; Chiosis, G.
Journal of Neurochemistry (2021)

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Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

Journal Article

Joshi, S.; Gomes, E. D.; Wang, T.; Corben, A.; Taldone, T.; Gandu, S.; Xu, C.; Sharma, S.; Buddaseth, S.; Yan, P.; more...
Communications Biology (2021)

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Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

Journal Article

Bolaender, A.; Zatorska, D.; He, H.; Joshi, S.; Sharma, S.; Digwal, C. S.; Patel, H. J.; Sun, W.; Imber, B. S.; Ochiana, S. O.; more...
Nature Communications (2021)

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Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia

Journal Article

Sugita, M.; Wilkes, D. C.; Bareja, R.; Eng, K. W.; Nataraj, S.; Jimenez-Flores, R. A.; Yan, L. B.; De Leon, J. P.; Croyle, J. A.; Kaner, J.; more...
npj Precision Oncology (2021)

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Rational approaches for the design of various GABA modulators and their clinical progression

Review

Bhagat, K.; Singh, J. V.; Pagare, P. P.; Kumar, N.; Sharma, A.; Kaur, G.; Kinarivala, N.; Gandu, S.; Singh, H.; Sharma, S.; more...
Molecular Diversity (2021)

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Tailored quinolines demonstrate flexibility to exert antitumor effects through varied mechanisms - A medicinal perspective

Review

Sharma, S.; Singh, A.; Sharma, S.; Sharma, R.; Singh, J.; Kinarivala, N.; Nepali, K.; Liou, J. P.
Anti-Cancer Agents in Medicinal Chemistry (2021)

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Chemical probes and methods for single-cell detection and quantification of epichaperomes in hematologic malignancies

Journal Article

Merugu, S.; Sharma, S.; Kaner, J.; Digwal, C.; Sugita, M.; Joshi, S.; Taldone, T.; Guzman, M. L.; Chiosis, G.
Methods in Enzymology (2020)

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