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Ryan Nathan Ptashkin

Formats
  1. Meeting Abstract (41)
  2. Journal Article (38)
  3. Research Letter (4)
  4. Editorial (1)
  5. Review (1)
Groups
  1. Department of Pathology and Laboratory Medicine (79)
  2. GSK Faculty (78)
  3. Human Oncology and Pathogenesis Program (75)
  4. Department of Medicine (73)
  5. Center for Molecular Imaging and Biotechnology (CMIB) (68)
  6. Solid Tumor Oncology Division (58)

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People
  1. Michael Berger (52)
  2. Ahmet Zehir (49)
  3. Marc Ladanyi (42)
  4. Maria Arcila (31)
  5. Ross Levine (24)
  6. Ryma Benayed (23)

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Years
  1. 2025 (1)
  2. 2024 (3)
  3. 2023 (10)
  4. 2022 (15)
  5. 2021 (8)
  6. 2020 (15)

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Publications
  1. Journal of Clinical Oncology (9)
  2. Modern Pathology (9)
  3. Blood (8)
  4. Clinical Cancer Research (8)
  5. Cancer Research (6)
  6. Journal of Molecular Diagnostics (6)

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Publishers
  1. American Association for Cancer Research (16)
  2. American Society of Clinical Oncology (13)
  3. Nature Publishing Group (11)
  4. American Society of Hematology (10)
  5. Nature Research (9)
  6. Elsevier Science, Inc. (7)

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Results (85)

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  • A deep multiple instance learning framework improves microsatellite instability detection from tumor next generation sequencing
    Journal Article

    Ziegler, J.; Hechtman, J. F.; Rana, S.; Ptashkin, R. N.; Jayakumaran, G.; Middha, S.; Chavan, S. S.; Vanderbilt, C.; DeLair, D.; Casanova, J.; more...
    Nature Communications (2025)

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  • Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies
    Journal Article

    Krystel-Whittemore, M.; Petrova-Drus, K.; Ptashkin, R. N.; Ewalt, M. D.; Yao, J.; Liu, Y.; Zhu, M.; Benhamida, J.; Durham, B.; Kumar, J.; more...
    Haematologica (2024)

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  • High-risk and silent clonal hematopoietic genotypes in patients with nonhematologic cancer
    Journal Article

    Stonestrom, A. J.; Menghrajani, K. N.; Devlin, S. M.; Franch-Expósito, S.; Ptashkin, R. N.; Patel, S. Y.; Spitzer, B.; Wu, X.; Jee, J.; Vela, P. S.; more...
    Blood Advances (2024)

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  • Microsatellite instability and mismatch repair deficiency define a distinct subset of lung cancers characterized by smoking exposure, high tumor mutational burden, and recurrent somatic MLH1 inactivation
    Journal Article

    Yang, S. R.; Gedvilaite, E.; Ptashkin, R.; Chang, J.; Ziegler, J.; Mata, D. A.; Villafania, L. B.; Nafa, K.; Hechtman, J. F.; Benayed, R.; more...
    Journal of Thoracic Oncology (2024)

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  • Associations between cancer predisposition mutations and clonal hematopoiesis in patients with solid tumors
    Journal Article

    Franch-Expósito, S.; Mehine, M.; Ptashkin, R. N.; Bolton, K. L.; Bandlamudi, C.; Srinivasan, P.; Zhang, L.; Goodell, M. A.; Gedvilaite, E.; Menghrajani, K.; more...
    JCO Precision Oncology (2023)

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  • Prevalence and clinical implications of mismatch repair-proficient colorectal cancer in patients with Lynch syndrome
    Journal Article

    Ranganathan, M.; Sacca, R. E.; Trottier, M.; Maio, A.; Kemel, Y.; Salo-Mullen, E.; Catchings, A.; Kane, S.; Wang, C.; Ravichandran, V.; more...
    JCO Precision Oncology (2023)

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  • CDKN2A/B mutations and allele-specific alterations stratify survival outcomes in IDH-mutant astrocytomas
    Research Letter

    Hickman, R. A.; Gedvilaite, E.; Ptashkin, R.; Reiner, A. S.; Cimera, R.; Nandakumar, S.; Price, A.; Vanderbilt, C.; Fahy, T.; Young, R. J.; more...
    Acta Neuropathologica (2023)

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  • Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing
    Journal Article

    Ptashkin, R. N.; Ewalt, M. D.; Jayakumaran, G.; Kiecka, I.; Bowman, A. S.; Yao, J. J.; Casanova, J.; Lin, Y. T. D.; Petrova-Drus, K.; Mohanty, A. S.; more...
    Nature Communications (2023)

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  • Allele-specific loss or mutations in CDKN2A/B worsen overall survival in IDH-mutant astrocytomas
    Meeting Abstract

    Hickman, R.; Gedvilaite, E.; Ptashkin, R.; Cimera, R.; Vanderbilt, C.; Benhamida, J.; Fahy, T.; Young, R.; Miller, A.; Mellinghoff, I.; more...
    Journal of Neuropathology and Experimental Neurology (2023)

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  • IDH-mutant astrocytomas with primitive neuronal component are aggressive tumors characterized by alterations in RB1 and TP53
    Meeting Abstract

    Slocum, C.; Hickman, R.; Gedvilaite, E.; Ptashkin, R.; Brannon, R.; Ladanyi, M.; Miller, A.; Pentsova, E.; Tabar, V.; Young, R.; more...
    Journal of Neuropathology and Experimental Neurology (2023)

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