CDKN2A/B mutations and allele-specific alterations stratify survival outcomes in IDH-mutant astrocytomas Research Letter

   

Authors:	Hickman, R. A.; Gedvilaite, E.; Ptashkin, R.; Reiner, A. S.; Cimera, R.; Nandakumar, S.; Price, A.; Vanderbilt, C.; Fahy, T.; Young, R. J.; Miller, A. M.; Mellinghoff, I. K.; Rosenblum, M. K.; Ladanyi, M.; Arcila, M. E.; Zhang, Y.; Brannon, A. R.; Bale, T. A.
Title:	CDKN2A/B mutations and allele-specific alterations stratify survival outcomes in IDH-mutant astrocytomas
Keywords:	gene mutation; major clinical study; overall survival; gene deletion; genetics; mutation; note; brain tumor; glioma; brain neoplasms; allele; cohort analysis; alleles; heterozygosity loss; cyclin dependent kinase inhibitor 2a; cyclin-dependent kinase inhibitor p16; astrocytoma; isocitrate dehydrogenase; copy number variation; cyclin dependent kinase inhibitor 2b; humans; human; tumor mutational burden; cdkn2a protein, human; idh mutant astrocytoma
Journal Title:	Acta Neuropathologica
Volume:	146
Issue:	6
ISSN:	0001-6322
Publisher:	Springer
Date Published:	2023-12-01
Start Page:	845
End Page:	847
Language:	English
DOI:	10.1007/s00401-023-02639-0
PUBMED:	37831210
PROVIDER:	scopus
PMCID:	PMC10628020
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85174147202&doi=10.1007%2fs00401-023-02639-0&partnerID=40&md5=5c6285c5a7ca2a96a1a2ae866ff07c64
Notes:	The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Tejus A. Bale -- Source: Scopus

https://synapse.mskcc.org/synapse/works/has_related_data_chk/211524