Authors: | Hickman, R. A.; Gedvilaite, E.; Ptashkin, R.; Reiner, A. S.; Cimera, R.; Nandakumar, S.; Price, A.; Vanderbilt, C.; Fahy, T.; Young, R. J.; Miller, A. M.; Mellinghoff, I. K.; Rosenblum, M. K.; Ladanyi, M.; Arcila, M. E.; Zhang, Y.; Brannon, A. R.; Bale, T. A. |
Title: | CDKN2A/B mutations and allele-specific alterations stratify survival outcomes in IDH-mutant astrocytomas |
Keywords: | gene mutation; major clinical study; overall survival; gene deletion; genetics; mutation; note; brain tumor; glioma; brain neoplasms; allele; cohort analysis; alleles; heterozygosity loss; cyclin dependent kinase inhibitor 2a; cyclin-dependent kinase inhibitor p16; astrocytoma; isocitrate dehydrogenase; copy number variation; cyclin dependent kinase inhibitor 2b; humans; human; tumor mutational burden; cdkn2a protein, human; idh mutant astrocytoma |
Journal Title: | Acta Neuropathologica |
Volume: | 146 |
Issue: | 6 |
ISSN: | 0001-6322 |
Publisher: | Springer |
Date Published: | 2023-12-01 |
Start Page: | 845 |
End Page: | 847 |
Language: | English |
DOI: | 10.1007/s00401-023-02639-0 |
PUBMED: | 37831210 |
PROVIDER: | scopus |
PMCID: | PMC10628020 |
DOI/URL: | |
Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Tejus A. Bale -- Source: Scopus |