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Cristina C Clement

Formats
  1. Journal Article (9)
  2. Meeting Abstract (3)
Groups
  1. Center for Hematologic Malignancies (12)
  2. GSK Faculty (12)
  3. Hematologic Malignancies Research (12)
  4. Molecular Pharmacology and Chemistry Program Faculty (12)
  5. Sloan Kettering Institute Faculty (12)
  6. Sloan Kettering Institute Postdocs (8)

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People
  1. Gabriela Chiosis (12)
  2. Anna Rodina Balingcongan (8)
  3. Yanlong Kang (8)
  4. Julia Aguirre (6)
  5. Alexander Gozman (5)
  6. Tony Taldone (5)

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Years
  1. 2014 (2)
  2. 2011 (2)
  3. 2010 (1)
  4. 2009 (1)
  5. 2008 (2)
  6. 2007 (2)

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Publications
  1. Bioorganic & Medicinal Chemistry Letters (2)
  2. Journal of Medicinal Chemistry (2)
  3. Abstracts of Papers of the American Chemical Society (1)
  4. Assay and Drug Development Technologies (1)
  5. Cancer Cell (1)
  6. Cancer Research (1)

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Publishers
  1. American Chemical Society (3)
  2. Pergamon-Elsevier Science Ltd (2)
  3. American Association for Cancer Research (1)
  4. Cell Press (1)
  5. Federation of American Societies for Experimental Biology (1)
  6. Mary Ann Liebert, Inc (1)

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Results (12)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • Heat shock protein 70 inhibitors. 2. 2,5′-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70
    Journal Article

    Taldone, T.; Kang, Y.; Patel, H. J.; Patel, M. R.; Patel, P. D.; Rodina, A.; Patel, Y.; Gozman, A.; Maharaj, R.; Clement, C. C.; more...
    Journal of Medicinal Chemistry (2014)

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  • Heat shock protein 70 inhibitors. 1. 2,5′-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70
    Journal Article

    Kang, Y.; Taldone, T.; Patel, H. J.; Patel, P. D.; Rodina, A.; Gozman, A.; Maharaj, R.; Clement, C. C.; Patel, M. R.; Brodsky, J. L.; more...
    Journal of Medicinal Chemistry (2014)

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  • YK5 is a novel dual Hsc/Hsp70 inhibitor that is selective for tumor Hsp70 and is a valuable lead for the development of molecules with therapeutic potential in breast cancer
    Meeting Abstract

    Taldone, Tony; Kang, Yanlong; Rodina, Anna; Maharaj, Ronnie; Gozman, Alexander; Cerchietti, Leandro; Wong, Michael J. H.; Baaklini, Imad; Caldas Lopes, Eloisi; Patel, Hardik J.; more...
    Abstracts of Papers of the American Chemical Society (2011)

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  • Design of a flexible cell-based assay for the evaluation of heat shock protein 70 expression modulators
    Journal Article

    Ahn, J. H.; Luo, W.; Kim, J.; Rodina, A.; Clement, C. C.; Aguirre, J.; Sun, W.; Kang, Y.; Maharaj, R.; Moulick, K.; more...
    Assay and Drug Development Technologies (2011)

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  • YK5, a novel dual Hsc70 and Hsp70 inhibitor, is selective for tumor Hsp70 and has potent but selective activity in cancer cells
    Meeting Abstract

    Rodina, A.; Kang, Y.; Maharaj, R.; Gozman, A.; Taldone, T.; Cerchietti, L.; Wong, M. J. H.; Baaklini, I.; Caldas-Lopes, E.; Clement, C. C.; more...
    Cancer Research (2010)

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  • Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
    Journal Article

    Caldas-Lopes, E.; Cerchietti, L.; Ahn, J. H.; Clement, C. C.; Robles, A. I.; Rodina, A.; Moulick, K.; Taldone, T.; Gozman, A.; Guo, Y.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2009)

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  • Design of a fluorescence polarization assay platform for the study of human Hsp70
    Journal Article

    Kang, Y.; Taldone, T.; Clement, C. C.; Fewell, S. W.; Aguirre, J.; Brodsky, J. L.; Chiosis, G.
    Bioorganic & Medicinal Chemistry Letters (2008)

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  • The yeast Hsp110, Sse1p, exhibits high-affinity peptide binding
    Journal Article

    Goeckeler, J. L.; Petruso, A. P.; Aguirre, J.; Clement, C. C.; Chiosis, G.; Brodsky, J. L.
    FEBS Letters (2008)

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  • The yeast Hsp110, Sse1p, binds peptide with high affinity and plays a role in clathrin function
    Meeting Abstract

    Goeckeler, J. L.; Petruso, A. P.; Aguirre, J.; Clement, C.; Chiosis, G.; Brodsky, J. L.
    FASEB Journal (2007)

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  • Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer
    Journal Article

    Rodina, A.; Vilenchik, M.; Moulick, K.; Aguirre, J.; Kim, J.; Chiang, A.; Litz, J.; Clement, C. C.; Kang, Y.; She, Y.; more...
    Nature Chemical Biology (2007)

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