Research Focus

Former Employee. Structural Biology; Research Asst

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1. A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA

   Journal Article

   Yuan, Y. R.; Pei, Y.; Chen, H. Y.; Tuschl, T.; Patel, D. J.
   Structure (2006)

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2. Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

   Journal Article

   Yuan, Y. R.; Pei, Y.; Ma, J. B. ; Kuryavyi, V.; Zhadina, M.; Meister, G.; Chen, H. Y.; Dauter, Z.; Tuschl, T.; Patel, D. J.
   Molecular Cell (2005)

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