Research Focus

Former Employee. Research Facilities; Senior Research Scientist

Recent additions – View all

1. A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human dicer

   Journal Article

   Tian, Y.; Simanshu, D. K.; Ma, J. B. ; Park, J. E.; Heo, I.; Kim, V. N.; Patel, D. J.
   Molecular Cell (2014)

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2. Structural basis for piRNA 2′-O-methylated 3′-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains

   Journal Article

   Tian, Y.; Simanshu, D. K.; Ma, J. B. ; Patel, D. J.
   Proceedings of the National Academy of Sciences of the United States of America (2011)

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3. Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

   Journal Article

   Yuan, Y. R.; Pei, Y.; Ma, J. B. ; Kuryavyi, V.; Zhadina, M.; Meister, G.; Chen, H. Y.; Dauter, Z.; Tuschl, T.; Patel, D. J.
   Molecular Cell (2005)

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