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Dorothea Dimitrova Robev

Formats
  1. Journal Article (15)
  2. Review (1)
Groups
  1. GSK Faculty (16)
  2. Sloan Kettering Institute Faculty (16)
  3. Structural Biology Program Faculty (16)
  4. Sloan Kettering Institute Postdocs (9)
  5. Radiochemistry and Imaging Sciences Service (1)
  6. Radiology, Department of (1)
People
  1. Dimitar Nikolov (16)
  2. Juha Himanen (8)
  3. Kai Xu (5)
  4. Nayanendu Saha (5)
  5. Yehuda Goldgur (4)
  6. William Barton (3)

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Years
  1. 2023 (1)
  2. 2022 (1)
  3. 2021 (2)
  4. 2019 (1)
  5. 2018 (1)
  6. 2015 (1)

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Publications
  1. Proceedings of the National Academy of Sciences of the United States of America (2)
  2. Structure (2)
  3. Biomedicine and Pharmacotherapy (1)
  4. Cancer Letters (1)
  5. EMBO Journal (1)
  6. Genes and Development (1)

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Publishers
  1. Cell Press (3)
  2. Elsevier Inc. (2)
  3. National Academy of Sciences (2)
  4. Wiley Blackwell (2)
  5. American Association for the Advancement of Science (1)
  6. Cold Spring Harbor Laboratory Press (1)

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Results (16)

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  • Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells
    Journal Article

    Saha, N.; Baek, D. S.; Mendoza, R. P.; Robev, D.; Xu, Y.; Goldgur, Y.; De La Cruz, M. J.; de Stanchina, E.; Janes, P. W.; Xu, K.; more...
    Biomedicine and Pharmacotherapy (2023)

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  • Inhibitory monoclonal antibody targeting ADAM17 expressed on cancer cells
    Journal Article

    Saha, N.; Xu, K.; Zhu, Z.; Robev, D.; Kalidindi, T.; Xu, Y.; Himanen, J.; de Stanchina, E.; Pillarsetty, N. V. K.; Dimitrov, D. S.; more...
    Translational Oncology (2022)

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  • The EphB2 receptor uses homotypic, head-to-tail interactions within its ectodomain as an autoinhibitory control mechanism
    Journal Article

    Xu, Y.; Robev, D.; Saha, N.; Wang, B.; Dalva, M. B.; Xu, K.; Himanen, J. P.; Nikolov, D. B.
    International Journal of Molecular Sciences (2021)

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  • Structure of the EphB6 receptor ectodomain
    Journal Article

    Mason, E. O.; Goldgur, Y.; Robev, D.; Freywald, A.; Nikolov, D. B.; Himanen, J. P.
    PLoS ONE (2021)

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  • ADAM proteases: Emerging role and targeting of the non-catalytic domains
    Review

    Saha, N.; Robev, D.; Himanen, J. P.; Nikolov, D. B.
    Cancer Letters (2019)

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  • Therapeutic potential of targeting the Eph/ephrin signaling complex
    Journal Article

    Saha, N.; Robev, D.; Mason, E. O.; Himanen, J. P.; Nikolov, D. B.
    International Journal of Biochemistry and Cell Biology (2018)

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  • The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation
    Journal Article

    Xu, K.; Olsen, O.; Tzvetkova Robev, D.; Tessier-Lavigne, M.; Nikolov, D. B.
    Genes and Development (2015)

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  • Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism
    Journal Article

    Xu, K.; Wu, Z.; Renier, N.; Antipenko, A.; Tzvetkova Robev, D.; Xu, Y.; Minchenko, M.; Nardi-Dei, V.; Rajashankar, K. R.; Himanen, J.; more...
    Science (2014)

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  • Crystal structures of Lgr4 and its complex with R-Spondin1
    Journal Article

    Xu, K.; Xu, Y.; Rajashankar, K. R.; Robev, D.; Nikolov, D. B.
    Structure (2013)

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  • Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5
    Journal Article

    Xu, K.; Tzvetkova Robev, D.; Xu, Y.; Goldgur, Y.; Chan, Y. P.; Himanen, J. P.; Nikolov, D. B.
    Proceedings of the National Academy of Sciences of the United States of America (2013)

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