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Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing

Meeting Abstract

Nafa, K.; Zehir, A.; Mitchell, T.; Borsu, L.; Singer, S.; Tap, W.; Oultache, A.; Ladanyi, M.; Hechtman, J.
Laboratory Investigation (2015)

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Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing

Meeting Abstract

Nafa, K.; Zehir, A.; Mitchell, T.; Borsu, L.; Singer, S.; Tap, W.; Oultache, A.; Ladanyi, M.; Hechtman, J.
Modern Pathology (2015)

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MLN0128, an ATP-competitive mTOR kinase inhibitor with potent in vitro and in vivo antitumor activity, as potential therapy for bone and soft-tissue sarcoma

Journal Article

Slotkin, E. K.; Patwardhan, P. P.; Vasudeva, S. D.; de Stanchina, E.; Tap, W. D.; Schwartz, G. K.
Molecular Cancer Therapeutics (2015)

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Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth

Journal Article

Ran, L.; Sirota, I.; Cao, Z.; Murphy, D.; Shukla, S.; Xie, Y.; Kaufmann, M. C.; Gao, D.; Zhu, S.; Rossi, F.; more...
Cancer Discovery (2015)

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Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment

Journal Article

D'Angelo, S. P.; Shoushtari, A. N.; Agaram, N. P.; Kuk, D.; Qin, L. X.; Carvajal, R. D.; Dickson, M. A.; Gounder, M.; Keohan, M. L.; Schwartz, G. K.; more...
Human Pathology (2015)

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Inhibition of vascular endothelial growth factor a and hypoxia-inducible factor 1α maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculature

Journal Article

Lee, H. J.; Yoon, C.; Park, D. J.; Kim, Y. J.; Schmidt, B.; Lee, Y. J.; Tap, W. D.; Eisinger-Mathason, T. S. K.; Choy, E.; Kirsch, D. G.; more...
International Journal of Radiation Oncology, Biology, Physics (2015)

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Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing

Journal Article

Hechtman, J. F.; Zehir, A.; Mitchell, T.; Borsu, L.; Singer, S.; Tap, W.; Oultache, A.; Ladanyi, M.; Nafa, K.
Genes Chromosomes and Cancer (2015)

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A pilot study of PLX3397, a selective colony-stimulating factor 1 receptor (CSF1R) kinase inhibitor, in pigmented villonodular synovitis (PVNS)

Meeting Abstract

Tap, W. D.; Anthony, S. P.; Chmielowski, B.; Staddon, A. P.; Cohn, A. L.; Shapiro, G.; Puzanov, I.; Kwak, E. L.; Wagner, A. J.; Peterfy, C.; more...
Journal of Clinical Oncology (2014)

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Combined KIT and CTLA-4 blockade in patients with refractory GIST and other advanced sarcomas

Meeting Abstract

Shoushtari, A. N.; D'Angelo, S. P.; Keohan, M. L.; Dickson, M. A.; Gounder, M. M.; Abdullah, A. K.; Erinjeri, J. P.; Bluth, M. J.; Ustoyev, Y.; Condy, M. M.; more...
Journal of Clinical Oncology (2014)

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Predictors of overall survival in patients diagnosed with desmoplastic small round cell tumor (DSRCT)

Meeting Abstract

Shoushtari, A. N.; Qin, L. X.; Kuk, D.; Magnan, H. D.; Modak, S.; Wolden, S. L.; Cho, E. J.; Pallos, V.; Grubman, O.; Viny, A. D.; more...
Journal of Clinical Oncology (2014)

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