Improved dose uniformity for radioactive stents in endovascular brachytherapy Conference Paper

  


Author: Amols, H. I.
Editors: Kappas, C.; DelGuerra, A.; Kolitsi, Z.; Damilakis, Y.; Theodorou, K.
Title: Improved dose uniformity for radioactive stents in endovascular brachytherapy
Conference Title: 6th International Conference on Medical Physics
Abstract: Beta emitting P-32 stents are being tested in Intravascular Brachytherapy (IVB) as a method for reducing restenosis and improving the success rate of Percutaneous Transluminal Coronary Angioplasty (PTCA). It is well known that radioactive stents yield inhomogeneous dose distributions, with lower doses delivered to tissues in between stent struts, at the ends of the stent, and also at depth. It is hypothesized that dose inhomogeneity at the ends of a stent may contribute to treatment: failure or 'candy wrapper effect'. We present improved dose distributions for various design radioactive stents and compare dose distributions for beta stents vs. gamma stents; 'dumbbell' radioactive loaded stents vs. uniformly loaded stents; and stents with alternate strut design. It is demonstrated that dose inhomogenieties can be reduced by better stent design and isotope selection.
Keywords: therapy
Journal Title Patras Medical Physics 99
Conference Dates: 1999 Sep 1-4
Conference Location: Patras, Greece
ISBN: 9788832309010
Publisher: Monduzzi Editore  
Location: Bologna, Italy
Date Published: 1999-01-01
Start Page: 65
End Page: 71
Language: English
ACCESSION: WOS:000088407900009
PROVIDER: wos
Notes: Proceedings Paper -- VIth International Conference on Medical Physics -- SEP 01-04, 1999 -- PATRAS, GREECE -- Source: Wos