| Authors: |
Engert, A.; Balduini, C.; Brand, A.; Coiffier, B.; Cordonnier, C.; Döhner, H.; De Wit, T. D.; Eichinger, S.; Fibbe, W.; Green, T.; De Haas, F.; Iolascon, A.; Jaffredo, T.; Rodeghiero, F.; Sall Es, G.; Schuringa, J. J.; André, M.; Andre-Schmutz, I.; Bacigalupo, A.; Bochud, P. Y.; Den Boer, M.; Bonini, C.; Camaschella, C.; Cant, A.; Cappellini, M. D.; Cazzola, M.; Celso, C. L.; Dimopoulos, M.; Douay, L.; Dzierzak, E.; Einsele, H.; Ferreri, A.; De Franceschi, L.; Gaulard, P.; Gottgens, B.; Greinacher, A.; Gresele, P.; Gribben, J.; De Haan, G.; Hansen, J. B.; Hochhaus, A.; Kadir, R.; Kaveri, S.; Kouskoff, V.; Kühne, T.; Kyrle, P.; Ljungman, P.; Maschmeyer, G.; Méndez-Ferrer, S.; Milsom, M.; Mummery, C.; Ossenkoppele, G.; Pecci, A.; Peyvandi, F.; Philipsen, S.; Reitsma, P.; Ribera, J. M.; Risitano, A.; Rivella, S.; Ruf, W.; Schroeder, T.; Scully, M.; Socie, G.; Staal, F.; Stanworth, S.; Stauder, R.; Stilgenbauer, S.; Tamary, H.; Theilgaard-Mönch, K.; Thein, S. L.; Tilly, H.; Trneny, M.; Vainchenker, W.; Vannucchi, A. M.; Viscoli, C.; Vrielink, H.; Zaaijer, H.; Zanella, A.; Zolla, L.; Zwaginga, J. J.; Martinez, P. A.; Van Den Akker, E.; Allard, S.; Anagnou, N.; Andolfo, I.; Andrau, J. C.; Angelucci, E.; Anstee, D.; Aurer, I.; Avet-Loiseau, H.; Aydinok, Y.; Bakchoul, T.; Balduini, A.; Barcellini, W.; Baruch, D.; Baruchel, A.; Bayry, J.; Bento, C.; Van Den Berg, A.; Bernardi, R.; Bianchi, P.; Bigas, A.; Biondi, A.; Bohonek, M.; Bonnet, D.; Borchmann, P.; Borregaard, N.; Brækkan, S.; Van Den Brink, M.; Brodin, E.; Bullinger, L.; Buske, C.; Butzeck, B.; Cammenga, J.; Campo, E.; Carbone, A.; Cervantes, F.; Cesaro, S.; Charbord, P.; Claas, F.; Cohen, H.; Conard, J.; Coppo, P.; Vives Corron, J. L.; Da Costa, L.; Davi, F.; Delwel, R.; Dianzani, I.; Domanović, D.; Donnelly, P.; Drnovšek, T. D.; Dreyling, M.; Du, M. Q.; Dufour, C.; Durand, C.; Efremov, D.; Eleftheriou, A.; Elion, J.; Emonts, M.; Engelhardt, M.; Ezine, S.; Falkenburg, F.; Favier, R.; Federico, M.; Fenaux, P.; Fitzgibbon, J.; Flygare, J.; Foà, R.; Forrester, L.; Galacteros, F.; Garagiola, I.; Gardiner, C.; Garraud, O.; Van Geet, C.; Geiger, H.; Geissler, J.; Germing, U.; Ghevaert, C.; Girelli, D.; Godeau, B.; Gökbuget, N.; Goldschmidt, H.; Goodeve, A.; Graf, T.; Graziadei, G.; Griesshammer, M.; Gruel, Y.; Guilhot, F.; Von Gunten, S.; Gyssens, I.; Halter, J.; Harrison, C.; Harteveld, C.; Hellström-Lindberg, E.; Hermine, O.; Higgs, D.; Hillmen, P.; Hirsch, H.; Hoskin, P.; Huls, G.; Inati, A.; Johnson, P.; Kattamis, A.; Kiefel, V.; Kleanthous, M.; Klump, H.; Krause, D.; Hovinga, J. K.; Lacaud, G.; Lacroix-Desmazes, S.; Landman-Parker, J.; Legouill, S.; Lenz, G.; Von Lilienfeld-Toal, M.; Von Lindern, M.; Lopez-Guillermo, A.; Lopriore, E.; Lozano, M.; Macintyre, E.; Makris, M.; Mannhalter, C.; Martens, J.; Mathas, S.; Matzdorff, A.; Medvinsky, A.; Menendez, P.; Migliaccio, A. R.; Miharada, K.; Mikulska, M.; Minard, V.; Montalbán, C.; De Montalembert, M.; Montserrat, E.; Morange, P. E.; Mountford, J.; Muckenthaler, M.; Müller-Tidow, C.; Mumford, A.; Nadel, B.; Navarro, J. T.; El Nemer, W.; Noizat-Pirenne, F.; O’Mahony, B.; Oldenburg, J.; Olsson, M.; Oostendorp, R.; Palumbo, A.; Passamonti, F.; Patient, R.; De Latour, R. P.; Pflumio, F.; Pierelli, L.; Piga, A.; Pollard, D.; Raaijmakers, M.; Radford, J.; Rambach, R.; Koneti Rao, A.; Raslova, H.; Rebulla, P.; Rees, D.; Ribrag, V.; Rijneveld, A.; Rinalducci, S.; Robak, T.; Roberts, I.; Rodrigues, C.; Rosendaal, F.; Rosenwald, A.; Rule, S.; Russo, R.; Saglio, G.; Sanchez, M.; Scharf, R. E.; Schlenke, P.; Semple, J.; Sierra, J.; So-Osman, C.; Soria, J. M.; Stamatopoulos, K.; Stegmayr, B.; Stunnenberg, H.; Swinkels, D.; Barata, J. P. T.; Taghon, T.; Taher, A.; Terpos, E.; Thachil, J.; Tissot, J. D.; Touw, I.; Toye, A.; Trappe, R.; Traverse-Glehen, A.; Unal, S.; Vaulont, S.; Viprakasit, V.; Vitolo, U.; Van Wijk, R.; Wójtowicz, A.; Zeerleder, S.; Zieger, B.; Research, E. H. A. Roadmap for European Hematology |
| Article Title: |
The European hematology association roadmap for european hematology research: A consensus document |
| Abstract: |
The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at ∈ European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better fu treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine ‘sections’ in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients. © 2016 Ferrata Storti Foundation. |
| Keywords: |
fludarabine; janus kinase 2; nonhuman; rituximab; cd34 antigen; mantle cell lymphoma; erythropoiesis; embryonic stem cell; cd40 ligand; transcription factor; cyclophosphamide; hemoglobin; hematopoietic stem cell transplantation; chronic myeloid leukemia; acute lymphoblastic leukemia; europe; epigenetics; medical research; kruppel like factor; hemolytic anemia; medical society; pluripotent stem cell; large cell lymphoma; blood clotting disorder; lymphopoiesis; cd5 antigen; follicular lymphoma; marginal zone lymphoma; burkitt lymphoma; myeloproliferative neoplasm; blood clotting factor 9; transcription factor gata 1; paroxysmal nocturnal hemoglobinuria; notch1 receptor; nk t cell lymphoma; blood clotting factor 8; classical hodgkin lymphoma; transcription factor runx1; stat protein; thrombopoietin; dna methyltransferase 3a; padgem protein; nucleophosmin; b lymphocyte receptor; janus kinase 1; myelopoiesis; cd20 antibody; next generation sequencing; idelalisib; ibrutinib; megakaryopoiesis; human; article; blackfan diamond anemia; obinutuzumab; venetoclax; blood clotting factor 12; growth differentiation factor; thrombocyte antigen; cell reprogramming technique; erythrocyte fragility; european hematology association; mesenchymal stem cell transplantation
|
| Journal Title: |
Haematologica
|
| Volume: |
101 |
| Issue: |
2 |
| ISSN: |
0390-6078 |
| Publisher: |
Ferrata Storti Foundation
|
| Date Published: |
2016-02-01 |
| Start Page: |
115 |
| End Page: |
208 |
| Language: |
English |
| DOI: |
10.3324/haematol.2015.136739
|
| PROVIDER: |
scopus
|
| PMCID: |
PMC4938336
|
| PUBMED: |
26819058
|
| DOI/URL: |
|
| Notes: |
Article -- Export Date: 1 September 2016 -- Source: Scopus |
