Toward concurrent testing for somatic and germline variants in cancer patients Journal Article


Author: Mandelker, D.
Article Title: Toward concurrent testing for somatic and germline variants in cancer patients
Abstract: Sequencing for somatic alterations in patients' tumors is being increasingly clinically implemented to detect mutations that may guide therapy. Germline analysis of a cohort of patients undergoing tumor sequencing with matched normal has revealed that a small but significant percentage of these patients have germline variants that confer cancer susceptibility. © 2016 AACR. © 2016 American Association for Cancer Research.
Journal Title: Clinical Cancer Research
Volume: 22
Issue: 16
ISSN: 1078-0432
Publisher: American Association for Cancer Research  
Date Published: 2016-08-15
Start Page: 3987
End Page: 3988
Language: English
DOI: 10.1158/1078-0432.ccr-16-1043
PROVIDER: scopus
PUBMED: 27307597
DOI/URL:
Notes: Article -- Export Date: 1 September 2016 -- Source: Scopus
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  1. Diana Lauren Mandelker
    178 Mandelker