Male urethral carcinoma: Analysis of treatment outcome Journal Article


Authors: Dalbagni, G.; Zhang, Z. F.; Lacombe, L.; Herr, H. W.
Article Title: Male urethral carcinoma: Analysis of treatment outcome
Abstract: Objectives. To evaluate our experience with primary carcinomas of the male urethra and to analyze the impact of tumor variables and treatment on overall, disease-specific, local recurrence-free, and metastasis-free survival. Methods. Between 1958 and 1996, we identified 46 men with primary carcinoma of the bulbar and anterior urethra. The median follow-up was 125 months (1 to 336). The patients were stratified by stage, nodal status, histologic type, treatment, type of surgery, site of disease, year at diagnosis, and smoking status. Results. The overall survival and disease- specific survival rates at 5 years were 42% and 50%, respectively. The recurrence-free survival and metastasis-free survival rates at 5 years were 51% and 56%, respectively. The overall survival rate was 83% for superficial disease versus 36% for invasive tumors. The overall survival rate was 26% for tumors of the bulbar urethra versus 69% for tumors of the anterior urethra. Conclusions. Current modalities of treatment are ineffective for local control and survival. New treatment strategies are needed for urethral cancer.
Keywords: adult; clinical article; controlled study; treatment outcome; aged; survival rate; cancer recurrence; cancer staging; metastasis; smoking; cystectomy; penis amputation; transurethral resection; urethra carcinoma; urethra surgery; human; male; priority journal; article
Journal Title: Urology
Volume: 53
Issue: 6
ISSN: 0090-4295
Publisher: Elsevier Science, Inc.  
Date Published: 1999-06-01
Start Page: 1126
End Page: 1132
Language: English
DOI: 10.1016/s0090-4295(98)00659-1
PUBMED: 10367840
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 16 August 2016 -- Source: Scopus
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  1. Guido Dalbagni
    325 Dalbagni
  2. Harry W Herr
    594 Herr
  3. Louis Lacombe
    19 Lacombe