Female urethral carcinoma: An analysis of treatment outcome and a plea for a standardized management strategy Journal Article
| Authors: | Dalbagni, G.; Zhang, Z. F.; Lacombe, L.; Herr, H. W. |
| Article Title: | Female urethral carcinoma: An analysis of treatment outcome and a plea for a standardized management strategy |
| Abstract: | Objective. To evaluate our experience with primary carcinomas of the female urethra, by analysing the impact of tumour variables and treatment on overall, disease-specific, local recurrence- and metastasis-free survival. Patients and methods. Between 1958 and 1994, 72 women (median age 60 years, mean 59, range 21-84) with primary urethral carcinoma were identified. They were followed for a median (range) of 85 (0-384) months. The patients were stratified by stage, nodal status, histology, treatment, type of surgery, site of disease, year of diagnosis and smoking habit. Results. In a univariate analysis, stage, nodal status, type of surgery and site of the disease were important factors for survival and recurrence. In a multivariate analysis, primary stage, nodal status and site of disease were independent predictors of survival. Conclusion. Current modalities of treatment are ineffective for local control and survival; new treatment strategies are needed for female urethral cancers. |
| Keywords: | adult; cancer survival; treatment outcome; aged; aged, 80 and over; disease-free survival; middle aged; major clinical study; cancer recurrence; combined modality therapy; treatment; follow-up studies; neoplasm recurrence, local; risk factors; carcinoma; clinical protocols; brachytherapy; outcome; multivariate analysis; urethra; urethra carcinoma; urethral neoplasms; humans; human; female; priority journal; article |
| Journal Title: | British Journal of Urology |
| Volume: | 82 |
| Issue: | 6 |
| ISSN: | 0007-1331 |
| Publisher: | Wiley Blackwell |
| Date Published: | 1998-12-01 |
| Start Page: | 835 |
| End Page: | 841 |
| Language: | English |
| DOI: | 10.1046/j.1464-410X.1998.00878.x |
| PUBMED: | 9883221 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 12 December 2016 -- Source: Scopus |
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