Volumetric reduction of a choroid plexus carcinoma using preoperative chemotherapy Journal Article
| Authors: | Souweidane, M. M.; Johnson Jr, J. H.; Lis, E. |
| Article Title: | Volumetric reduction of a choroid plexus carcinoma using preoperative chemotherapy |
| Abstract: | We report for the first time a measured volumetric reduction of a choroid plexus carcinoma utilizing preoperative chemotherapy. Histologically proven choroid plexus carcinoma was diagnosed in a fifteen month old female. She was treated with three courses of chemotherapy including etoposide (VP16), cyclophosphamide, vincristine, and cisplatin. Computer-assisted three dimensional reconstruction of the tumor volume was performed prior to and after three courses of chemotherapy. An overall reduction of 29.5% of tumor volume was accomplished preoperatively. Staged surgical procedures resulted in a complete resection of her lesion and she has remained disease-free for 31 months. A volumetric measurement as a response to preoperative chemotherapy may prove valuable in determining future optimal treatment regimens for choroid plexus carcinoma of childhood. |
| Keywords: | preschool child; treatment outcome; disease-free survival; clinical feature; case report; cisplatin; combined modality therapy; nuclear magnetic resonance imaging; tumor volume; etoposide; antineoplastic combined chemotherapy protocols; tomography, x-ray computed; cyclophosphamide; vincristine; infant; three dimensional imaging; preoperative treatment; image processing, computer-assisted; second look surgery; choroid plexus tumor; intravenous drug administration; preoperative chemotherapy; choroid plexus carcinoma; choroid plexus neoplasms; humans; human; female; article; chemotherapy kinetics |
| Journal Title: | Journal of Neuro-Oncology |
| Volume: | 43 |
| Issue: | 2 |
| ISSN: | 0167-594X |
| Publisher: | Springer |
| Date Published: | 1999-06-01 |
| Start Page: | 167 |
| End Page: | 171 |
| Language: | English |
| DOI: | 10.1023/a:1006229732653 |
| PUBMED: | 10533729 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 16 August 2016 -- Source: Scopus |
