Long-term cardiac and pulmonary complications of cancer therapy Journal Article


Authors: Yahalom, J.; Portlock, C. S.
Article Title: Long-term cardiac and pulmonary complications of cancer therapy
Abstract: Cardiac complications resulting from chemotherapy and radiation pose a significant risk for morbidity and mortality to the cancer survivor. Cardiac side effects may progress over time and are a concern for patients treated during childhood. Long-term pulmonary complications are relatively infrequent, and acute respiratory effects of drugs (mostly bleomycin) or radiation normally resolve early after therapy. Although most cardiovascular risk statistics and clinical experience are derived from patients treated before 1985, the modern radiation approach that limits the exposure of the heart and reduces the total dose seems to attenuate the previously observed cardiovascular risk. Potential preventive measures for high-risk patients are of increasing interest but remain experimental. © 2011 Elsevier Inc.
Keywords: radiotherapy; trastuzumab; anthracyclines; taxanes; cardiac toxicity; pulmonary toxicity
Journal Title: Heart Failure Clinics
Volume: 7
Issue: 3
ISSN: 1551-7136
Publisher: Elsevier Inc.  
Date Published: 2011-07-01
Start Page: 403
End Page: 411
Language: English
DOI: 10.1016/j.hfc.2011.04.002
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 17 August 2011" - "Source: Scopus"
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  1. Joachim Yahalom
    625 Yahalom
  2. Carol Portlock
    204 Portlock