Colonic manifestations of multiple endocrine neoplasia type 2B: Report of four cases Journal Article


Authors: Grobmyer, S. R.; Guillem, J. G.; O'Riordain, D. S.; Woodruff, J. M.; Shriver, C.; Brennan, M. F.
Article Title: Colonic manifestations of multiple endocrine neoplasia type 2B: Report of four cases
Abstract: Multiple endocrine neoplasia type 2B is best known for its endocrine manifestations and typical phenotype. The gastrointestinal manifestations, however, are also an important and commonly unrecognized component of the syndrome. We present four cases that demonstrate the varied presentation of patients with colonic manifestations of multiple endocrine neoplasia type 2B. We discuss the cause, diagnostic significance, and management of the colonic disease that is a component of multiple endocrine neoplasia type 2B.
Keywords: adolescent; adult; clinical feature; constipation; histopathology; case report; neurofibromatosis; abdominal pain; hyperplasia; surgery; colon perforation; gastrointestinal tract; pheochromocytoma; metoclopramide; ganglioneuroma; colon; abdominal distension; colon mucosa; megacolon; colonic diseases; humans; human; male; female; article; ganglioneuromatosis; colonic pseudo-obstruction; multiple endocrine neoplasia type 2b
Journal Title: Diseases of the Colon and Rectum
Volume: 42
Issue: 9
ISSN: 0012-3706
Publisher: Lippincott Williams & Wilkins  
Date Published: 1999-09-01
Start Page: 1216
End Page: 1219
Language: English
DOI: 10.1007/bf02238578
PUBMED: 10496565
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 16 August 2016 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Murray F Brennan
    1059 Brennan
  2. Jose Guillem
    414 Guillem
  3. James M Woodruff
    162 Woodruff