Radiofrequency ablation of non-small-cell carcinoma of the lung under real-time FDG PET CT guidance Journal Article

  


Authors: Schoellnast, H.; Larson, S. M.; Nehmeh, S. A.; Carrasquillo, J. A.; Thornton, R. H.; Solomon, S. B.
Article Title: Radiofrequency ablation of non-small-cell carcinoma of the lung under real-time FDG PET CT guidance
Abstract: Radiofrequency ablation (RFA) is a well-established method in treatment of patients with lung carcinomas who are not candidates for surgical resection. Usually computed tomographic (CT) guidance is used for the procedure, thus enabling needle placement and permitting evaluation of complications such as pneumothorax and bleeding. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is generally used for tumor activity assessment and is therefore useful in follow-up after tumor treatment. A method that provides real-time image-based monitoring of RFA to ensure complete tumor ablation would be a valuable tool. In this report, we describe the behavior of preinjected FDG during PET CT-guided RFA of a non-small-cell lung carcinoma and discuss the value of FDG as a tool to provide intraprocedure monitor ablation. The size and the form of the activity changed during ablation. Ablation led to increase of the size and blurring and irregularity of the contour compared to pretreatment imaging. The maximal standardized uptake value decreased only slightly during the procedure. Therefore, before RFA, FDG PET can guide initial needle placement, but it does not serve as a monitoring tool to evaluate residual viable tissue during the procedure. © Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2010.
Keywords: positron emission tomography; monitoring; radiofrequency ablation; tumor ablation; fdg pet; rfa
Journal Title: CardioVascular and Interventional Radiology
Volume: 34
Issue: Suppl. 2
ISSN: 0174-1551
Publisher: Springer  
Date Published: 2011-02-01
Start Page: S182
End Page: S185
Language: English
DOI: 10.1007/s00270-010-9898-7
PROVIDER: scopus
PUBMED: 20508937
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-79959705832&partnerID=40&md5=aac1758f26a64e78fde9edff0c51d2e1
Notes: --- - "Export Date: 17 August 2011" - "CODEN: CARAD" - "Source: Scopus"
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MSK Authors
  1. Helmut Schoellnast
    8 Schoellnast
  2. Stephen Solomon
    422 Solomon
  3. Raymond H Thornton
    84 Thornton
  4. Sadek Nehmeh
    69 Nehmeh
  5. Jorge Carrasquillo
    140 Carrasquillo
  6. Steven M Larson
    958 Larson
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