Complete sequences of mcr-1-harboring plasmids from extended-spectrum-β-lactamase- and carbapenemase-producing Enterobacteriaceae Journal Article
| Authors: | Li, A.; Yang, Y.; Miao, M.; Chavda, K. D.; Mediavilla, J. R.; Xie, X.; Feng, P.; Tang, Y. W.; Kreiswirth, B. N.; Chen, L.; Du, H. |
| Article Title: | Complete sequences of mcr-1-harboring plasmids from extended-spectrum-β-lactamase- and carbapenemase-producing Enterobacteriaceae |
| Abstract: | Here we completely sequenced four mcr-1-haboring plasmids, isolated from two extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli and two carbapenemase-producing Klebsiella pneumoniae clinical isolates. The mcr-1-harboring plasmids from an E. coli sequence type 2448 (ST2448) isolate and two K. pneumoniae ST25 isolates were identical (all pMCR1-IncX4), belonging to the IncX4 incompatibility group, while the plasmid from an E. coli ST2085 isolate (pMCR1-IncI2) belongs to the IncI2 group. A nearly identical 2.6-kb mcr-1-pap2 element was found to be shared by all mcr-1-carrying plasmids. Copyright © 2016, American Society for Microbiology. All Rights Reserved. |
| Journal Title: | Antimicrobial Agents and Chemotherapy |
| Volume: | 60 |
| Issue: | 7 |
| ISSN: | 0066-4804 |
| Publisher: | American Society for Microbiology |
| Date Published: | 2016-07-01 |
| Start Page: | 4351 |
| End Page: | 4354 |
| Language: | English |
| DOI: | 10.1128/aac.00550-16 |
| PROVIDER: | scopus |
| PMCID: | PMC4914624 |
| PUBMED: | 27090180 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 2 August 2016 -- Source: Scopus |
