Physiology of the hypothalamic pituitary gonadal axis in the male Journal Article
| Authors: | Corradi, P. F.; Corradi, R. B.; Greene, L. W. |
| Article Title: | Physiology of the hypothalamic pituitary gonadal axis in the male |
| Abstract: | Testosterone synthesis and male fertility are the results of the perfect coordination of the hypothalamic-pituitary-gonadal axis. A negative feedback finely controls the secretion of hormones at the 3 levels. Congenital or acquired disturbance at any level leads to an impairment of reproductive function and the clinical syndrome of hypogonadism. In some cases, this condition is reversible. Once the diagnosis is made, testosterone replacement therapy is the standard therapy; however, novel therapies may improve spermatogenesis while elevating testosterone levels. |
| Keywords: | gonadotropin; hypogonadism; testosterone; sexual function; hypogonadotropic hypogonadism; androgen insensitivity syndrome; testosterone levels; older men; serum testosterone; luteinizing-hormone; secondary hypogonadism; primary hypogonadism; gonadotropin-releasing-hormone; idiopathic hypogonadotropic hypogonadism; normal men; hpg mouse |
| Journal Title: | Urologic Clinics of North America |
| Volume: | 43 |
| Issue: | 2 |
| ISSN: | 0094-0143 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2016-05-01 |
| Start Page: | 151 |
| End Page: | 162 |
| Language: | English |
| ACCESSION: | WOS:000376792400003 |
| DOI: | 10.1016/j.ucl.2016.01.001 |
| PROVIDER: | wos |
| PUBMED: | 27132572 |
| Notes: | Article -- Source: Wos |
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