Authors: | Kirane, A.; Crago, A. M. |
Article Title: | The importance of surgical margins in retroperitoneal sarcoma |
Abstract: | Surgery is the "gold-standard" treatment for retroperitoneal sarcomas, but local recurrence is common, and can cause disease-related death. Complete gross resection is associated with improved survival, but debate exists as to whether resection of adjacent organs to improve margins or prescription of neoadjuvant radiation leads to better outcomes. This review summarizes data addressing prognostic value of margin, extent of surgery necessary to optimize treatment of retroperitoneal sarcomas, and role of histology in optimizing therapy. (c) 2015 Wiley Periodicals, Inc. |
Keywords: | survival; recurrence; leiomyosarcoma; liposarcoma; soft-tissue sarcoma; prognostic-significance; resection predict pattern; histologic subtype; beam radiation-therapy; extended; intermediate-grade; retroperitoneal sarcoma; extended surgery; compartment resection |
Journal Title: | Journal of Surgical Oncology |
Volume: | 113 |
Issue: | 3 |
ISSN: | 0022-4790 |
Publisher: | Wiley Blackwell |
Date Published: | 2016-03-01 |
Start Page: | 270 |
End Page: | 276 |
Language: | English |
ACCESSION: | WOS:000374502900005 |
DOI: | 10.1002/jso.24135 |
PROVIDER: | wos |
PUBMED: | 26707028 |
Notes: | Review -- SI -- Source: Wos |