DROSHA and DICER: Slicers cut from the same cloth Journal Article
| Authors: | Li, S.; Patel, D. J. |
| Article Title: | DROSHA and DICER: Slicers cut from the same cloth |
| Abstract: | DROSHA and its partner DGCR8 form a heterotrimeric complex named Microprocessor, which is essential for microRNA biogenesis. A recent study by Kwon et al. in Cell reveals the structure of a DROSHA construct in complex with the C-terminal region of DGCR8, thereby unveiling the topology and interactions between components of the Microprocessor and insights into its 'ruler'-based cleavage activity and function. © 2016 IBCB, SIBS, CAS. |
| Journal Title: | Cell Research |
| Volume: | 26 |
| Issue: | 5 |
| ISSN: | 1001-0602 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2016-05-01 |
| Start Page: | 511 |
| End Page: | 512 |
| Language: | English |
| DOI: | 10.1038/cr.2016.19 |
| PROVIDER: | scopus |
| PMCID: | PMC4856758 |
| PUBMED: | 27125999 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 2 June 2016 -- Source: Scopus |
