rcellminer: Exploring molecular profiles and drug response of the NCI-60 cell lines in R Journal Article
| Authors: | Luna, A.; Rajapakse, V. N.; Sousa, F. G.; Gao, J.; Schultz, N.; Varma, S.; Reinhold, W.; Sander, C.; Pommier, Y. |
| Article Title: | rcellminer: Exploring molecular profiles and drug response of the NCI-60 cell lines in R |
| Abstract: | Purpose: The rcellminer R package provides a wide range of functionality to help R users access and explore molecular profiling and drug response data for the NCI-60. The package enables flexible programmatic access to CellMiner's unparalleled breadth of NCI-60 data, including gene and protein expression, copy number, whole exome mutations, as well as activity data for ∼21K compounds, with information on their structure, mechanism of action and repeat screens. Functions are available to easily visualize compound structures, activity patterns and molecular feature profiles. Additionally, embedded R Shiny applications allow interactive data exploration. © 2015 Published by Oxford University Press. |
| Journal Title: | Bioinformatics |
| Volume: | 32 |
| Issue: | 8 |
| ISSN: | 1367-4803 |
| Publisher: | Oxford University Press |
| Date Published: | 2016-04-15 |
| Start Page: | 1272 |
| End Page: | 1274 |
| Language: | English |
| DOI: | 10.1093/bioinformatics/btv701 |
| PROVIDER: | scopus |
| PUBMED: | 26635141 |
| PMCID: | PMC4907377 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 2 June 2016 -- Source: Scopus |
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