Using a population-based analysis to determine the management and treatment of early-stage small-cell lung cancer Journal Article


Author: Pietanza, M. C.
Article Title: Using a population-based analysis to determine the management and treatment of early-stage small-cell lung cancer
Abstract: Decades of randomized clinical trials have led to the development of a clear treatment approach for patients with limited-stage or extensive-stage small-cell lung cancer (SCLC). The standard first-line chemotherapy regimen is cisplatin or carboplatin plus etoposide, with the addition of radiation therapy for patients with limited-stage SCLC whose cancer is confined to the chest in a single tolerable radiation field. Patients with limited- And extensive-stage SCLC who demonstrate a response to first-line platinum-based therapy generally are offered prophylactic cranial irradiation (PCI), which has been shown to decrease the risk of intracranial recurrence and improve overall survival. ©2016 American Society of Clinical Oncology.
Journal Title: Journal of Clinical Oncology
Volume: 34
Issue: 10
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 2016-04-01
Start Page: 1027
End Page: 1029
Language: English
DOI: 10.1200/jco.2015.65.6462
PROVIDER: scopus
PUBMED: 26884572
DOI/URL:
Notes: Editorial -- Export Date: 2 May 2016 -- Source: Scopus
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  1. Maria C Pietanza
    120 Pietanza
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