Diffusion tensor imaging in the normal breast: Influences of fibroglandular tissue composition and background parenchymal enhancement Journal Article

   

Authors:	Plaza, M. J.; Morris, E. A.; Thakur, S. B.
Article Title:	Diffusion tensor imaging in the normal breast: Influences of fibroglandular tissue composition and background parenchymal enhancement
Abstract:	Objective: To evaluate effects of fibroglandular tissue (FGT) composition and background parenchymal enhancement (BPE) on diffusion tensor imaging (DTI) parameters in normal breast tissue. Methods: DTI analysis was performed on 35 breasts with regions of interest drawn to include only normal tissue. Breasts were dichotomized by FGT composition and by BPE; DTI parameters were compared. Results: The λ1 principal diffusion coefficient was lower in breasts with moderate/marked BPE versus those with minimal/mild BPE (P=.039). All other parameters were unaffected. Conclusion: λ1 is sensitive to differences in BPE within normal breast tissue that should be taken into account in DTI evaluation. © 2015 Elsevier Inc.
Keywords:	breast; diffusion; mri; dti; tensor
Journal Title:	Clinical Imaging
Volume:	40
Issue:	3
ISSN:	0899-7071
Publisher:	Elsevier Inc.
Date Published:	2016-05-01
Start Page:	506
End Page:	511
Language:	English
DOI:	10.1016/j.clinimag.2015.12.001
PROVIDER:	scopus
PMCID:	PMC4853756
PUBMED:	27133695
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84959256752&partnerID=40&md5=f64c511cd43744a04281a00808225d6a
Notes:	Article -- Export Date: 4 April 2016 -- Source: Scopus

https://synapse.mskcc.org/synapse/works/has_related_data_chk/90336