Overcoming antigen escape with CAR T-cell therapy Journal Article
| Authors: | Jackson, H. J.; Brentjens, R. J. |
| Article Title: | Overcoming antigen escape with CAR T-cell therapy |
| Abstract: | Sotillo and colleagues describe the molecular events associated with apparent loss of target antigen expression following CAR T-cell therapy. We propose that broader immune activation is required to prevent outgrowth of tumor antigen escape variants following targeted therapies. © 2015 American Association for Cancer Research. |
| Journal Title: | Cancer Discovery |
| Volume: | 5 |
| Issue: | 12 |
| ISSN: | 2159-8274 |
| Publisher: | American Association for Cancer Research |
| Date Published: | 2015-12-01 |
| Start Page: | 1238 |
| End Page: | 1240 |
| Language: | English |
| DOI: | 10.1158/2159-8290.cd-15-1275 |
| PROVIDER: | scopus |
| PUBMED: | 26637657 |
| PMCID: | PMC5536095 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 4 April 2016 -- Source: Scopus |
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