Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius Journal Article


Authors: Rosenfeld, J. A.; Reeves, D.; Brugler, M. R.; Narechania, A.; Simon, S.; Durrett, R.; Foox, J.; Shianna, K.; Schatz, M. C.; Gandara, J.; Afshinnekoo, E.; Lam, E. T.; Hastie, A. R.; Chan, S.; Cao, H.; Saghbini, M.; Kentsis, A.; Planet, P. J.; Kholodovych, V.; Tessler, M.; Baker, R.; DeSalle, R.; Sorkin, L. N.; Kolokotronis, S. O.; Siddall, M. E.; Amato, G.; Mason, C. E.
Article Title: Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius
Abstract: The common bed bug (Cimex lectularius) has been a persistent pest of humans for thousands of years, yet the genetic basis of the bed bug's basic biology and adaptation to dense human environments is largely unknown. Here we report the assembly, annotation and phylogenetic mapping of the 697.9-Mb Cimex lectularius genome, with an N50 of 971 kb, using both long and short read technologies. A RNA-seq time course across all five developmental stages and male and female adults generated 36,985 coding and noncoding gene models. The most pronounced change in gene expression during the life cycle occurs after feeding on human blood and included genes from the Wolbachia endosymbiont, which shows a simultaneous and coordinated host/commensal response to haematophagous activity. These data provide a rich genetic resource for mapping activity and density of C. lectularius across human hosts and cities, which can help track, manage and control bed bug infestations. © 2016, Nature Publishing Group. All rights reserved.
Keywords: cimex lectularius; cimicidae; wolbachia
Journal Title: Nature Communications
Volume: 7
ISSN: 2041-1723
Publisher: Nature Publishing Group  
Date Published: 2016-02-02
Start Page: 10164
Language: English
DOI: 10.1038/ncomms10164
PROVIDER: scopus
PMCID: PMC4740774
PUBMED: 26836631
DOI/URL:
Notes: Article -- Export Date: 3 March 2016 -- Source: Scopus
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  1. Alex   Kentsis
    47 Kentsis