Results of the National Lung Cancer Screening Trial: Where are we now? Journal Article
| Authors: | Chudgar, N. P.; Bucciarelli, P. R.; Jeffries, E. M.; Rizk, N. P.; Park, B. J.; Adusumilli, P. S.; Jones, D. R. |
| Article Title: | Results of the National Lung Cancer Screening Trial: Where are we now? |
| Abstract: | The National Lung Screening Trial was a large, multicenter, randomized controlled trial published in 2011. It found that annual screening with low-dose CT (LDCT) in a high-risk population was associated with a 20% reduction in lung cancer-specific mortality compared with conventional chest radiography. Several leading professional organizations have since put forth lung cancer screening guidelines that include the use of LDCT, largely on the basis of this study. Broad adoption of these screening recommendations, however, remains a challenge. Copyright © 2015 Elsevier Inc. All rights reserved. |
| Keywords: | controlled study; aged; middle aged; clinical trial; mortality; comparative study; radiation dose; sensitivity and specificity; computer assisted tomography; randomized controlled trial; lung neoplasms; lung cancer; mass screening; tomography, x-ray computed; pathology; radiation exposure; radiation dosage; radiography, thoracic; lung tumor; early diagnosis; screening; multicenter study; radiography; thorax radiography; early detection of cancer; adverse effects; procedures; low-dose ct; humans; human; statistics and numerical data; nlst |
| Journal Title: | Thoracic Surgery Clinics |
| Volume: | 25 |
| Issue: | 2 |
| ISSN: | 1547-4127 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2015-05-01 |
| Start Page: | 145 |
| End Page: | 153 |
| Language: | English |
| DOI: | 10.1016/j.thorsurg.2014.11.002 |
| PUBMED: | 25901558 |
| PROVIDER: | scopus |
| PMCID: | PMC4817217 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 3 February 2016 -- Source: Scopus |
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