Recommendations for implementing lung cancer screening with low-dose computed tomography in Europe Review
| Authors: | Veronesi, G.; Baldwin, D. R.; Henschke, C. I.; Ghislandi, S.; Iavicoli, S.; Oudkerk, M.; De Koning, H. J.; Shemesh, J.; Field, J. K.; Zulueta, J. J.; Horgan, D.; Navarrete, L. F.; Infante, M. V.; Novellis, P.; Murray, R. L.; Peled, N.; Rampinelli, C.; Rocco, G.; Rzyman, W.; Scagliotti, G. V.; Tammemagi, M. C.; Bertolaccini, L.; Triphuridet, N.; Yip, R.; Rossi, A.; Senan, S.; Ferrante, G.; Brain, K.; van der Aalst, C.; Bonomo, L.; Consonni, D.; Van Meerbeeck, J. P.; Maisonneuve, P.; Novello, S.; Devaraj, A.; Saghir, Z.; Pelosi, G. |
| Review Title: | Recommendations for implementing lung cancer screening with low-dose computed tomography in Europe |
| Abstract: | Lung cancer screening (LCS) with low-dose computed tomography (LDCT) was demonstrated in the National Lung Screening Trial (NLST) to reduce mortality from the disease. European mortality data has recently become available from the Nelson randomised controlled trial, which confirmed lung cancer mortality reductions by 26% in men and 39–61% in women. Recent studies in Europe and the USA also showed positive results in screening workers exposed to asbestos. All European experts attending the “Initiative for European Lung Screening (IELS)”—a large international group of physicians and other experts concerned with lung cancer—agreed that LDCT-LCS should be implemented in Europe. However, the economic impact of LDCT-LCS and guidelines for its effective and safe implementation still need to be formulated. To this purpose, the IELS was asked to prepare recommendations to implement LCS and examine outstanding issues. A subgroup carried out a comprehensive literature review on LDCT-LCS and presented findings at a meeting held in Milan in November 2018. The present recommendations reflect that consensus was reached. © 2020 by the authors. Licensee MDPI, Basel, Switzerland. |
| Keywords: | mortality; cancer risk; radiation dose; demography; consensus; computer assisted tomography; cancer screening; lung cancer; smoking cessation; smoking; practice guideline; prediction; risk assessment; self report; netherlands; health care policy; cost effectiveness analysis; health care cost; health program; population research; screening; incidental finding; false positive result; quality adjusted life year; low dose; computed tomography; chronic obstructive lung disease; volumetry; reduction; asbestos; lung emphysema; implementation; statement; low dose computed tomography; human; article; coronary artery calcification |
| Journal Title: | Cancers |
| Volume: | 12 |
| Issue: | 6 |
| ISSN: | 2072-6694 |
| Publisher: | MDPI |
| Date Published: | 2020-06-01 |
| Start Page: | 1672 |
| Language: | English |
| DOI: | 10.3390/cancers12061672 |
| PROVIDER: | scopus |
| PMCID: | PMC7352874 |
| PUBMED: | 32599792 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 3 August 2020 -- Source: Scopus |
