Authors: | Rørth, M.; Rajpert-De Meyts, E.; Andersson, L.; Dieckmann, K. P.; Fosså, S. D.; Grigor, K. M.; Hendry, W. F.; Herr, H. W.; Looijenga, L. H. J.; Oosterhuis, J. W.; Skakkebaek, N. E. |
Article Title: | Carcinoma in situ in the testis |
Abstract: | Carcinoma in situ (CIS) of the testis is a common precursor of germ-cell tumours in adults and adolescents, with the exception of spermatocytic seminoma. This article reviews existing knowledge on the pathobiology, genetic aspects and epidemiology of CIS, discusses current hypotheses concerning pathogenesis and invasive progression of germ-cell neoplasms and provides guidelines for diagnosis and clinical management of CIS. |
Keywords: | adolescent; adult; genetics; histopathology; review; conference paper; cancer radiotherapy; comparative study; radiation dose; neoplasm; spermatocyte; cell structure; germ cell; radiotherapy; incidence; prevalence; tumor markers, biological; cytogenetics; practice guideline; pathology; tumor marker; stem cell; cell transformation, neoplastic; cancer invasion; cancer genetics; cell transformation; carcinoma in situ; testis tumor; testicular neoplasms; cross-sectional study; cross-sectional studies; neoplasms, germ cell and embryonal; orchiectomy; cancer classification; testis cancer; malignant transformation; germ cell tumor; testis; seminoma; cultural factor; practice guidelines; humans; human; male; priority journal; orchidectomy; cross-cultural comparison; isochromosome i(p12); testicular biopsy; testicular development |
Journal Title: | Scandinavian Journal of Urology and Nephrology, Supplement |
Volume: | 34 |
Issue: | Suppl. 205 |
ISSN: | 0300-8886 |
Publisher: | Taylor & Francis Group |
Date Published: | 2000-01-01 |
Start Page: | 166 |
End Page: | 186 |
Language: | English |
PUBMED: | 11144894 |
PROVIDER: | scopus |
DOI: | 10.1080/00365590050509896 |
DOI/URL: | |
Notes: | Export Date: 18 November 2015 -- Source: Scopus |