The long-term complications of chemotherapy in childhood genitourinary tumors Journal Article


Authors: Sklar, C. A.; LaQuaglia, M. P.
Article Title: The long-term complications of chemotherapy in childhood genitourinary tumors
Abstract: Combination chemotherapy, often in conjunction with surgery and external radiotherapy, is utilized in most children with tumors of the genitourinary tract. These chemotherapeutic agents are capable of causing a variety of delayed toxicities. Common late complications include cardiotoxicity associated with prior exposure to an anthracycline, pulmonary dysfunction, infertility in males due to prior therapy with alkylating agents, and secondary leukemia in individuals treated with epipodophyllotoxins.
Keywords: cancer chemotherapy; child; review; antineoplastic agents; liver dysfunction; lung toxicity; drug effect; urogenital neoplasms; ovary; kidney; cardiotoxicity; urinary bladder; lung; urogenital tract tumor; anthracycline; hemorrhagic cystitis; testis; male infertility; humans; human; male; female; priority journal
Journal Title: Urologic Clinics of North America
Volume: 27
Issue: 3
ISSN: 0094-0143
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 2000-08-01
Start Page: 563
End Page: 568
Language: English
PUBMED: 10985155
PROVIDER: scopus
DOI: 10.1016/S0094-0143(05)70103-8
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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  1. Charles A Sklar
    322 Sklar