PriA-directed replication fork restart in Escherichia coli Journal Article


Author: Marians, K. J.
Article Title: PriA-directed replication fork restart in Escherichia coli
Abstract: The encounter of a replication fork with either a damaged DNA template, a nick in the template strand or a 'frozen' protein-DNA complex can stall the replisome and cause it to fall apart. Such an event generates a requirement for replication fork restart if the cell is going to survive. Recent evidence shows that replication fork restart is effected by the action of the recombination proteins generating a substrate for PriA-directed replication fork assembly. Copyright (C) 2000 Elsevier Science Ltd.
Keywords: unclassified drug; dna-binding proteins; review; nonhuman; dna replication; chromosome; phenotype; dna damage; cell survival; escherichia coli; helicase; replication protein a; chromosomes, bacterial; reca protein; dna template; dna protein complex; priority journal; pria protein
Journal Title: Trends in Biochemical Sciences
Volume: 25
Issue: 4
ISSN: 0968-0004
Publisher: Elsevier Inc.  
Date Published: 2000-04-01
Start Page: 185
End Page: 189
Language: English
DOI: 10.1016/s0968-0004(00)01565-6
PUBMED: 10754552
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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  1. Kenneth Marians
    138 Marians