How cells read TGF-β signals Journal Article
| Author: | Massagué, J. |
| Article Title: | How cells read TGF-β signals |
| Abstract: | Cell proliferation, differentiation and death are controlled by a multitude of cell-cell signals, and loss of this control has devastating consequences. Prominent among these regulatory signals is the transforming growth factor-β (TGF-β) family of cytokines, which can trigger a bewildering diversity of responses, depending on the genetic makeup and environment of the target cell. What are the networks of cell-specific molecules that mould the TGF-β response to each cell's needs? |
| Keywords: | signal transduction; review; animal; animals; cell division; biological model; models, biological; map kinase signaling system; transforming growth factor beta; physiology; chemistry; transforming growth factor beta receptor; receptors, transforming growth factor beta; humans; human |
| Journal Title: | Nature Reviews Molecular Cell Biology |
| Volume: | 1 |
| Issue: | 3 |
| ISSN: | 1471-0072 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2000-12-01 |
| Start Page: | 169 |
| End Page: | 178 |
| Language: | English |
| PUBMED: | 11252892 |
| PROVIDER: | scopus |
| DOI: | 10.1038/35043051 |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
