Complexity and specificity of integrin signalling Journal Article


Author: Giancotti, F. G.
Article Title: Complexity and specificity of integrin signalling
Abstract: The α-subunits of integrins - transmembrane adhesion proteins - associate with particular transmembrane and cytoplasmic proteins, providing a mechanism for the activation of specific intracellular signalling pathways by individual integrins.
Keywords: signal transduction; mitogen activated protein kinase; nonhuman; amino acid substitution; protein protein interaction; vascular cell adhesion molecule 1; enzyme activation; extracellular matrix; cell migration; fibroblast; short survey; protein kinase c; conformational transition; alpha chain; cell adhesion; cytoskeleton; focal adhesion kinase; integrin; integrins; fibronectin; thrombospondin; mucosal addressin cell adhesion molecule 1; beta chain; fibrinogen receptor; paxillin; caveolin; phosphatidylinositol kinase; cell spreading; talin; human; priority journal; alpha actinin
Journal Title: Nature Cell Biology
Volume: 2
Issue: 1
ISSN: 1465-7392
Publisher: Nature Publishing Group  
Date Published: 2000-01-01
Start Page: E13
End Page: E14
Language: English
DOI: 10.1038/71397
PUBMED: 10620816
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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