The chemistry and immunochemistry of blood group A, B, H, and Lewis antigens: Past, present and future Journal Article
| Author: | Lloyd, K. O. |
| Article Title: | The chemistry and immunochemistry of blood group A, B, H, and Lewis antigens: Past, present and future |
| Abstract: | This article traces reseach on the chemistry and immunochemistry of blood group A, B, H, and Lewis antigens from early work on the identification of soluble sources of these antigens, through the elucidation of the structures of the carbohydrate epitopes responsible for these specificities, to recent work on exploring their possible use as cancer vaccines. The various approaches used in the isolation of oligosaccharides from mucins for use in structural studies are discussed, as are recent efforts in the chemical systhesis of blood group-active oligosaccharides. |
| Keywords: | human cell; review; united states; neoplasms; cancer immunotherapy; blood group abo system; abo blood-group system; tumor antigen; history, 20th century; amino acid sequence; molecular sequence data; cancer vaccine; tumor antigens; antigen detection; epitope mapping; structure analysis; polysaccharides; glycoproteins; carbohydrate analysis; carbohydrate sequence; immunochemistry; lewis blood-group system; mucin; mucins; glycolipids; epitopes; oligosaccharides; oligosaccharide synthesis; blood group lewis system; humans; human; priority journal; autobiography; blood group antigens; alkaline elimination; blood group a antigen; blood group b antigen; blood group o antigen; blood group system |
| Journal Title: | Glycoconjugate Journal |
| Volume: | 17 |
| Issue: | 7-9 |
| ISSN: | 0282-0080 |
| Publisher: | Springer New York LLC |
| Date Published: | 2000-07-01 |
| Start Page: | 531 |
| End Page: | 541 |
| Language: | English |
| DOI: | 10.1023/a:1011066308591 |
| PUBMED: | 11421346 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
