Complex surgical strategies to improve resectability in borderline-resectable disease Journal Article


Authors: Qadan, M.; D'Angelica, M. I.
Article Title: Complex surgical strategies to improve resectability in borderline-resectable disease
Abstract: Colorectal cancer is the third most common malignancy in the USA and continues to pose a significant epidemiologic problem, despite major advances in the treatment of patients with advanced disease. Up to 50 % of patients will develop metastatic disease at some point during the course of their disease, with the liver being the most common site of metastatic disease. In this review, we address the relatively poorly defined entity of borderline-resectable colorectal liver metastases. The workup and staging of borderline-resectable disease are discussed. We then discuss management strategies, including surgical techniques and medical therapies, which are currently utilized in order to improve resectability. © 2015, Springer Science+Business Media New York.
Keywords: colorectal cancer; liver resection; hepatectomy; colorectal liver metastases; ablation; systemic chemotherapy; portal vein embolization; borderline; future liver remnant; borderline-resectable; hepatic arterial infusion pump; two-stage hepatectomy
Journal Title: Current Colorectal Cancer Reports
Volume: 11
Issue: 6
ISSN: 1556-3790
Publisher: Springer  
Date Published: 2015-12-01
Start Page: 369
End Page: 377
Language: English
DOI: 10.1007/s11888-015-0290-5
PROVIDER: scopus
PMCID: PMC5231889
PUBMED: 28090195
DOI/URL:
Notes: Export Date: 2 December 2015 -- Source: Scopus
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  1. Motaz   Qadan
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