Finding the genes that direct mammalian development: ENU mutagenesis in the mouse Journal Article
| Author: | Anderson, K. V. |
| Article Title: | Finding the genes that direct mammalian development: ENU mutagenesis in the mouse |
| Abstract: | The genetic control of mammalian embryogenesis is not well understood. N-ethyl-N-nitrosourea (ENU) mutagenesis screens in the mouse provide a route to identify more of the genes that are required for mammalian development. The characterization of ENU-induced mutations can build on the resources provided by the mouse and human genome projects to help define the tissue interactions and signaling pathways that direct early mammalian development. Copyright (C) 2000 Elsevier Science Ltd. |
| Keywords: | mutation; nonhuman; mouse; phenotype; mammalia; animals; mice; genes; embryo; animal experiment; mice, mutant strains; embryo development; gene expression regulation, developmental; species specificity; genome; mammals; genetic screening; ethylnitrosourea; mutagenesis; mutant; chromosome mapping; abnormalities; genetic regulation; mutagenicity; humans; priority journal; article; embryonic and fetal development |
| Journal Title: | Trends in Genetics |
| Volume: | 16 |
| Issue: | 3 |
| ISSN: | 0168-9525 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2000-03-01 |
| Start Page: | 99 |
| End Page: | 102 |
| Language: | English |
| DOI: | 10.1016/s0168-9525(99)01921-6 |
| PUBMED: | 10689347 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
