Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies Journal Article
| Authors: | Rojas, I.; Graus, F.; Keime-Guibert, F.; Reñé, R.; Delattre, J. Y.; Ramón, J. M.; Dalmau, J.; Posner, J. B. |
| Article Title: | Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies |
| Abstract: | The outcome of 34 women with anti-Yo-associated paraneoplastic cerebellar degeneration was reviewed. Three patients had not developed cancer after more than 4 years of follow-up. The only independent predictor for survival was the type of associated tumor (risk ratio, 1.79; 95% CI, 1.02 to 3.12). Median survival was 100 months for patients with breast cancer and 22 for those with gynecologic cancer. Although paraneoplastic cerebellar degeneration leads to the diagnosis of cancer in 63% of the patients, cancer progression was the cause of death in 52%. |
| Keywords: | adult; cancer survival; clinical article; aged; middle aged; survival analysis; unclassified drug; cancer growth; cancer diagnosis; disease association; breast cancer; breast neoplasms; time factors; genital neoplasms, female; paraneoplastic syndrome; gynecologic cancer; antibody; paraneoplastic cerebellar degeneration; cerebellum degeneration; yo antibody; humans; prognosis; human; female; priority journal; article |
| Journal Title: | Neurology |
| Volume: | 55 |
| Issue: | 5 |
| ISSN: | 0028-3878 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2000-09-12 |
| Start Page: | 713 |
| End Page: | 715 |
| Language: | English |
| PUBMED: | 10980743 |
| PROVIDER: | scopus |
| DOI: | 10.1212/WNL.55.5.713 |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
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