Status epilepticus with neuron-reactive serum antibodies: Response to plasma exchange Journal Article
| Authors: | Lousa, M.; Sanchez-Alonso, S.; Rodriguez-Diaz, R.; Dalmau, J. |
| Article Title: | Status epilepticus with neuron-reactive serum antibodies: Response to plasma exchange |
| Abstract: | The authors report a patient with partial and secondarily generalized status epilepticus who required 70 days of general anesthesia for seizure control. Although antiepileptic medications failed to control the seizures, they resolved with plasma exchange. The patient's serum reacted with rat cerebral cortex, hippocampus, and cerebellum, but not with cells expressing the glutamate receptor GluR3. These findings suggest an immune response against neuronal antigens other than GluR3. |
| Keywords: | adolescent; treatment outcome; clinical feature; case report; animals; plasmapheresis; immune response; brain; general anesthesia; rats; antibodies; glutamate receptor; antibody detection; tomography, emission-computed, single-photon; epileptic state; anesthetic agent; receptor antibody; status epilepticus; humans; human; male; priority journal; article; cell antigen; antibodies to glur3; plasma exchange; rasmussen's encephalitis; epileptogenesis; receptors, ampa |
| Journal Title: | Neurology |
| Volume: | 54 |
| Issue: | 11 |
| ISSN: | 0028-3878 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2000-06-13 |
| Start Page: | 2163 |
| End Page: | 2165 |
| Language: | English |
| PUBMED: | 10851386 |
| PROVIDER: | scopus |
| DOI: | 10.1212/WNL.54.11.2153 |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
